June 2026 in “Advanced Healthcare Materials” This study introduces a taurine-based active pharmaceutical ingredient ionic liquid (CTIL) as a novel treatment for androgenic alopecia (AGA). CTIL is synthesized through a one-step method and functions both as a delivery carrier and a therapeutic agent. It effectively penetrates the skin barrier, targeting hair follicles to deliver antioxidants and modulate the perifollicular microenvironment by scavenging reactive oxygen species (ROS). In vitro studies show that CTIL's hydrogen-bond network structure enhances its penetration and accumulation in hair follicles. In an AGA animal model, CTIL reduced ROS, alleviated oxidative damage and inflammation, inhibited hair follicle miniaturization, and promoted hair regrowth. This research highlights the potential of bioactive ionic liquids in treating AGA by integrating delivery and therapeutic functions.
May 2015 in “Endocrinología y nutrición” The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.
April 2018 in “Journal of Investigative Dermatology” CENPV, a new partner of CYLD, helps regulate ciliary acetylated tubulin and is overexpressed in certain skin tumors.
27 citations
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September 1992 in “The Lancet” ICL is a condition with low CD4+ T cells like AIDS but not caused by HIV, and normal CD4+ T cell counts may vary between men and women.
4 citations
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January 2020
38 citations
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January 2016 in “Cell Death and Disease” The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
April 2007 in “Nature Clinical Practice Urology” TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.
3 citations
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November 1998 in “PubMed”
11 citations
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March 2024 in “Cell and Tissue Research” Telocytes have potential in therapy and tissue regeneration, but challenges in identification and cultivation remain.
March 2026 in “Journal of the American Academy of Dermatology” The treatment significantly improved lymphocytic cicatricial alopecia symptoms in most patients.
IL-18 signaling helps mature Tregs move into the thymus.
September 2023 in “Journal of the American Academy of Dermatology” CTP-543 is generally safe for treating alopecia areata.
April 2017 in “Journal of Investigative Dermatology” The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.
IL-18 signaling helps mature Tregs move into the thymus.
5 citations
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January 2021 in “Pakistan Journal of Nematology” Citrullus colocynthis is a valuable natural option for medicine and pest control.
33 citations
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June 2007 in “Gene Expression Patterns” CTIP2 may help in skin development and maintenance.
7 citations
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September 2024 in “The Journal of Dermatology” Ritlecitinib helps regrow hair in people with alopecia totalis and universalis and is safe to use.
January 2025 in “Organics” Micelles can change cetirizine's ionization, affecting its effectiveness in treatments.
40 citations
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December 2012 in “PLoS ONE” Removing Ctip2 in skin cells causes skin inflammation similar to atopic dermatitis.
7 citations
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May 2015 in “Journal of biological chemistry/The Journal of biological chemistry” Different ligands change the shape of the TRPV3 ion channel in unique ways.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Croton tiglium Linn. may promote hair growth but needs careful detoxification due to its toxicity.
33 citations
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August 2000 in “Experimental Cell Research” CCC1 is essential for ion balance and proper plant cell function.
September 2025 in “Journal of the American Academy of Dermatology” Ritlecitinib may help treat alopecia areata by protecting hair follicles.
55 citations
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June 2014 in “Nature Communications” Tcf3 helps cells move and heal wounds by controlling lipocalin 2.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Croton tiglium Linn. may promote hair growth but needs careful use due to toxicity.
October 1984 in “Immunology Today” 2 citations
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September 2023 in “Journal of the American Academy of Dermatology” CTP-543 effectively promotes hair regrowth in adults with moderate to severe alopecia areata.
October 2022 in “Amplla Editora eBooks” Tocilizumab might be an effective treatment for COVID-19.
November 2025 in “Journal of Investigative Dermatology” TEC kinases may help cause inflammation in vitiligo and could be targeted for treatment.