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Genetic Alteration of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase Subunit Expression Affects Calcium Currents and Beta-Endorphin Release in AtT-20 Clonal Pituitary Cells

research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.

August 1994 in “Molecular Endocrinology”

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

research Cytokeratin expression in trichoblastic fibroma (small nodular type trichoblastoma), trichoepithelioma and basal cell carcinoma

87 citations , January 1999 in “British Journal of Dermatology”

Trichoblastic fibroma and basal cell carcinoma are similar but different from trichoepithelioma.

research KRT17: A Key Driver of Cancer Therapy Resistance and Emerging Therapeutic Target

November 2025 in “Cancer Management and Research”

Targeting Keratin 17 may help overcome cancer therapy resistance.

research A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats

40 citations , June 2013 in “Scientific Reports”

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

research Reply to: The ends of a conundrum?

March 2007 in “Journal of Cell Science”

K10 may not prevent tumors as previously thought and might increase benign tumor risk.

research Protein Kinase C Epsilon Signals Ultraviolet Light‐induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism^¶

3 citations , January 2005 in “Photochemistry and Photobiology”

Protein kinase C epsilon may promote skin cancer development after UV exposure by affecting nearby cells.

research Radiofrequency Currents Modulate Inflammatory Processes in Keratinocytes

3 citations , October 2024 in “International Journal of Molecular Sciences”

CRET therapy affects inflammation in skin cells by changing cytokine levels and activating certain proteins.

research Signal integrator function of CXXC5 in Cancer

January 2025 in “Cell Communication and Signaling”

CXXC5 can both suppress and promote cancer, making it a complex target for treatment.

research Cytokeratin 15 expression in central, centrifugal, cicatricial alopecia: new observations in normal and diseased hair follicles

14 citations , January 2011 in “Journal of Cutaneous Pathology”

CK15 is not a reliable marker for stem cells in damaged hair follicles from patients with CCCA.

research Decision letter: Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1)

September 2021

CCC1 is essential for ion balance and proper plant cell function.

The N-K Healing Series: Complete Geometric Restoration for Wounds, Pain, and Burns Using N-K Universal Computer

research The N‑K Healing Series: Complete Geometric Restoration for Wounds, Pain, and Burns PAIN-GM1, REGEN-GM1, and BURN-GM1 — Complete Geometric Analysis Using N‑K Universal Computer, 1 Million Virtual Injuries Simulated, 100% Accuracy Comparison with Mainstream Medicine — Why Current Treatments Fail and How N‑K Geometry Succeeds

February 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

N-K Geometric Medicine heals wounds, pain, and burns better and faster than current treatments, without side effects.

research The N‑K Healing Series: Complete Geometric Restoration for Wounds, Pain, and Burns PAIN-GM1, REGEN-GM1, and BURN-GM1 — Complete Geometric Analysis Using N‑K Universal Computer, 1 Million Virtual Injuries Simulated, 100% Accuracy Comparison with Mainstream Medicine — Why Current Treatments Fail and How N‑K Geometry Succeeds

February 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

N-K Geometric Medicine heals wounds, pain, and burns better and faster than current treatments, without side effects.

research Protein Kinase C as a Therapeutic Target

87 citations , September 2006 in “Clinical Cancer Research”

Protein Kinase C shows promise for cancer treatment, but more research is needed to develop effective inhibitors.

research 268 Use of ultra-fast one-step CK5 ihc for identifying bcc and scc during mohs surgery

1 citations , April 2017 in “Journal of Investigative Dermatology”

A new one-step test can quickly identify skin cancer during surgery.

research Bidirectional binding property of high glycine–tyrosine keratin-associated protein contributes to the mechanical strength and shape of hair

46 citations , June 2013 in “Journal of structural biology”

High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.

research Inducible Cutaneous Inflammation Reveals a Protumorigenic Role for Keratinocyte CXCR2 in Skin Carcinogenesis

70 citations , December 2008 in “Cancer Research”

CXCR2 in skin cells promotes tumor growth.

research Selection of adult hair follicle stem cells and the effects of #beta#--catenin

January 2006 in “Chieh P'ou Hsueh Pao”

A method was found to select hair follicle stem cells, and beta-catenin helps them grow and change.

research Impaired Hair Follicle Morphogenesis and Cycling with Abnormal Epidermal Differentiation in nackt Mice, a Cathepsin L-Deficient Mutation

57 citations , August 2002 in “American Journal Of Pathology”

Cathepsin L deficiency causes hair and skin issues in mice.

research Protein Kinase C δ Overexpressing Transgenic Mice Are Resistant to Chemically but not to UV Radiation–Induced Development of Squamous Cell Carcinomas: A Possible Link to Specific Cytokines and Cyclooxygenase-2

35 citations , January 2006 in “Cancer Research”

Mice with extra PKCδ resist chemical-induced skin cancer but not UV-induced.

research Crosslinking structure of keratin. V. Number and type of crosslinks in microstructures of untreated and potassium cyanide treated human hair

11 citations , September 1996 in “Journal of applied polymer science”

Potassium cyanide treatment changes hair's disulfide bonds, making it more elastic.

A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels

research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels

5 citations , January 2018

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

research Characterization of tiger tail banding and hair shaft abnormalities in trichothiodystrophy

7 citations , March 2004 in “Journal of the American Academy of Dermatology”

Tiger tail banding and hair abnormalities are reliable indicators for diagnosing trichothiodystrophy.

research Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating

33 citations , May 2018 in “Stem Cell Reports”

Krt15+ cells in the mouse intestine resist radiation and can start tumors.

research CtBP1 Overexpression in Keratinocytes Perturbs Skin Homeostasis

9 citations , November 2013 in “Journal of Investigative Dermatology”

Overexpressing CtBP1 in skin cells causes skin and hair problems.

[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs

research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs

26 citations , July 2007 in “Biochemical Pharmacology”

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

research LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants

July 2025 in “Journal of Investigative Dermatology”

TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.

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