research Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen
The research identified new skin traits in mice, some linked to human skin conditions.
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research Emerging treatments in alopecia
New alopecia treatments aim for better results and fewer side effects.
research Top applications of dermatologic ultrasonography that can modify management
Ultrasonography in dermatology improves diagnosis and treatment of skin conditions.
research The evolution of healthy skin to acne lesions: a longitudinal, in vivo evaluation with reflectance confocal microscopy and optical coherence tomography
Acne lesions start with changes in hair follicles and increase in inflammation, suggesting a cycle that could affect treatment strategies.
research Sensitization to saw palmetto and minoxidil in separate topical extemporaneous treatments for androgenetic alopecia
Saw palmetto causes allergic reaction, minoxidil causes skin irritation; use cautiously for hair loss.
research Ruxolitinib found to cause eyelash growth: a case report
Ruxolitinib treatment may cause eyelash growth.
research Bioinformatics analysis of genes associated with the patchy-type alopecia areata: CD2 may be a new therapeutic target
CD2 might be a new treatment target for patchy alopecia areata.
research Manifestaciones clínicas y complicaciones de la enfermedad por coronavirus 2019 (COVID-19): revisión de la literatura
COVID-19 symptoms range from mild to severe, with older adults at higher risk.
research Skin manifestations of hyperandrogenism: an update
Targeting androgen receptors in the skin is the most effective treatment for hyperandrogenism-related skin issues.
research SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation
SPT6 prevents excessive skin inflammation by blocking a feedback loop.
research Scalp basal cell carcinoma: A different entity?
Scalp basal cell carcinoma may be more aggressive and harder to treat than other types, requiring special attention and further research.
research Teaching dermatosurgery
Dermatology residents need thorough training in dermatosurgery for better patient outcomes.
research Keratins in health and cancer: more than mere epithelial cell markers
Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
research The Rotterdam Study: 2018 update on objectives, design and main results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research The Rotterdam Study: 2016 objectives and design update
The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
research Anatomy and Physiology of the Skin
The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
research Melatonin in the skin: synthesis, metabolism and functions
Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
research Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin
Hair follicle development and microbes help regulatory T cells gather in newborn skin.
research Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
research Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection
Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
research Pharmacology of antiandrogens
Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
research Crafting Polymeric and Peptidic Hydrogels for Improved Wound Healing
Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
research Targeted gene delivery to skin cells in vivo: A comparative study of liposomes and polymers as delivery vehicles
Nonionic liposomes are the best for delivering genes to skin cells.
research From neural crest cells to melanocytes: cellular plasticity during development and beyond
Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
research Management of congenital ichthyoses: European guidelines of care, part two
European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.
research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor β2 Expression
Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
research Presentation, impact and prevention of chemotherapy-induced hair loss: scalp cooling potentials and limitations
Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.
research Recent advances in nanocarrier-loaded gels: Which drug delivery technologies against which diseases?
Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.
research Stem cell plasticity enables hair regeneration following Lgr5+ cell loss
Hair can regrow after certain stem cells are lost because other stem cells can take over their role.