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The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.

The C-allele and CC-genotype in the PTPN22 gene lower the risk of alopecia areata.

Finasteride increases P-glycoprotein activity in the liver and kidney.

Genetic variations may affect how well finasteride works for BPH patients.

Methylation in specific gene region causes finasteride resistance in some BPH patients.

Certain gene variations increase the risk of alopecia areata in Koreans.

Epristeride's metabolism involves key metabolites and proteins, affecting its use in doping tests.

New mutations in the EBP gene cause CDPX2, affecting bones, skin, eyes, and hair, with females generally less affected than males.

A new mutation in the LIPH gene was found to cause a rare hair disorder in a Japanese boy.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

Micelles can change cetirizine's ionization, affecting its effectiveness in treatments.

A new genetic mutation causing Xeroderma Pigmentosum was found in an 8-year-old girl, affecting her DNA repair.

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

Lack of cystatin M/E causes thin hair and dry skin.

A genetic marker linked to a type of hair loss was found in most patients studied.

The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.

CTP-543 is generally safe for treating alopecia areata.

Cantú syndrome is caused by mutations in the ABCC9 gene.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.

THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.

A new method accurately measures clobetasol propionate in hair and skin.

Certain variations in the vitamin D receptor gene are linked to an increased risk of polycystic ovary syndrome.

The treatment improved acne, seborrhoea, and hirsutism, with some side effects like spotting and nervousness.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

Lack of a key enzyme causes severe skin issues and death in mice.

Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.

Cytarabine can cause multiple organ toxicities, especially neurotoxicity, but better research methods are needed to fully understand and predict these effects.