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Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Finasteride may improve prostate cancer therapy by enhancing testosterone's benefits and reducing risks.

A new compound, 3a, effectively fights prostate cancer better than finasteride.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

Topical therapies show promise for hair loss and acne treatment with minimal side effects.

20(S)-Protopanaxadiol-aglycone may help prevent and treat prostate cancer by reducing androgen receptor activity.

Diphenylcyclopropenone is effective for treating alopecia areata but has a high relapse rate.

Fenugreek extract may help treat benign prostatic hyperplasia.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

Testosterone stimulates growth in intermediate hair follicles, but this can be blocked by cyproterone acetate.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Diphenylcyclopropenone is effective and safe for treating severe alopecia areata in children, with maintenance therapy reducing relapse risk.

Phytochemicals may offer safer alternatives to synthetic drugs for prostate cancer treatment.

Chlormadinone acetate is useful for birth control and treating various hormonal issues.

TGPC plus CGT is effective and safe for treating severe alopecia areata in children.

Cyclosporin A, a drug, reduces TGF-β2 expression in skin cells, potentially causing excessive hair growth through a process involving the calcineurin/NFAT pathway.

The medicine Diane is effective in treating hair loss, severe acne, and excessive hair growth.

Low-dose flutamide-metformin therapy effectively improved PCOS symptoms in adolescent girls.

New genes and pathways are important for testosterone production and male sexual development.

New compounds with carborane showed anti-androgen effects similar to flutamide.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

The compound 4c effectively inhibits the enzyme linked to hair loss.

The new compounds may be more effective and cheaper than current treatments for conditions like baldness.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.