research Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases
Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.
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720-750 / 1000+ resultsresearch When bugs and drugs conspire: driving acneiform skin toxicity
Certain cancer drugs interact with skin bacteria to cause acne-like rashes.
research Review of Promising Off-Label Use of Deucravacitinib
Deucravacitinib may help treat various immune diseases beyond psoriasis, but more research is needed.
research Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition
Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.
research Fibroblasts: Origins, definitions, and functions in health and disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System
Cannabinoids may help treat various skin conditions.
research An integrated model of alopecia areata biomarkers highlights both TH1 and TH2 upregulation
Alopecia areata severity is linked to increased TH1 and TH2 activity.
research Combination of lyophilized adipose-derived stem cell concentrated conditioned medium and polysaccharide hydrogel in the inhibition of hypertrophic scarring
The combination of stem cell medium and hydrogel effectively reduces and improves hypertrophic scars.
research <p>The regenerative potential of skin and the immune system</p>
The skin's immune system helps it regenerate and fight infections.
research Diverse Role of OX40 on T Cells as a Therapeutic Target for Skin Diseases
OX40-targeted therapies may help treat skin diseases by reducing inflammation and balancing immune responses.
research Extracellular vesicles from IFN-γ-primed mesenchymal stem cells repress atopic dermatitis in mice
Stem cell vesicles reduced eczema symptoms in mice safely.
research Mesenchymal Stem Cell Secretome for Dermatology Application: A Review
The secretome from mesenchymal stem cells shows promise for treating skin conditions and improving skin and hair health, but more research is needed.
research Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature
Developing human skin has immune cells with memory-like features.
research Developing a JAK Inhibitor for Targeted Local Delivery: Ruxolitinib Cream
Ruxolitinib cream effectively targets and treats inflammatory skin diseases.
research Clinical Application of Development of Nonantibiotic Macrolides That Correct Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases
Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.
research Preparation and Characterization of Ginger Peel Polysaccharide–Zn (II) Complexes and Evaluation of Anti-Inflammatory Activity
Ginger peel polysaccharides modified with zinc effectively reduce inflammation.
research Lifestyle Factors Involved in the Pathogenesis of Alopecia Areata
Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.
research Mesenchymal Stem Cells Antagonize IFN-Induced Proinflammatory Changes and Growth Inhibition Effects via Wnt/β-Catenin and JAK/STAT Pathway in Human Outer Root Sheath Cells and Hair Follicles
Mesenchymal stem cells may help treat hair loss by improving hair cell growth and reducing inflammation.
research Hair follicle-derived mesenchymal stem cells decrease alopecia areata mouse hair loss and reduce inflammation around the hair follicle
Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
research Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging
Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
research Acellular dermal matrix hydrogels promote healing of radiation-induced skin injury in a rat model
ADM hydrogels help heal radiation skin injuries.
research Immune Cells in Cutaneous Wound Healing: A Review of Functional Data from Animal Models
Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.
research Biologics in the management of childhood atopic dermatitis
Biologics, especially Dupilumab, are effective and safe for treating severe childhood eczema.
research Wound Microbiota and Its Impact on Wound Healing
Wound healing is greatly affected by the types of bacteria present, which can either help or hinder the process.
research Neurological Mechanisms Exploration and Therapeutic Targets in Segmental Vitiligo Accompanied by White Hair
Managing stress and nerve activity can help treat segmental vitiligo and white hair.
research Skin fibroblast functional heterogeneity in health and disease
Different types of skin fibroblasts have unique roles in skin health and disease.
research Genome-wide association study of atopic and autoimmune comorbidities in alopecia areata
Certain genes may be linked to autoimmune conditions in people with alopecia areata.
research Modulating the Gut–Skin Axis in Dermatological Diseases: Mechanisms and Clinical Applications of Probiotics, Prebiotics, Synbiotics, and Postbiotics
Certain probiotics can help improve skin conditions like atopic dermatitis, but more research is needed.
research Platelet-Rich Plasma (PRP): Molecular Mechanisms, Actions and Clinical Applications in Human Body
PRP shows promise in healing and regeneration but needs standardized protocols for consistent results.
research Multi-omics analyses, cell experiments, and network pharmacology tools identified key proteins and candidate drugs for alopecia areata treatment
Key proteins and potential drugs for treating alopecia areata were identified.