Understanding wound healing and signaling pathways could lead to new alopecia treatments.
March 2024 in “International journal of molecular sciences” Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.
Granzyme B accelerates skin aging and impairs healing by breaking down important skin components.
85 citations
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June 2017 in “Journal of Investigative Dermatology” Blimp1 is crucial for hair follicle growth and skin health.
20 citations
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November 2014 in “Developmental Dynamics” Palate formation and skin healing share similar biological processes.
November 2014 in “Hair transplant forum international” Hair restoration surgery in patients with prior neurosurgery or radiation treatment can have risks like infection and poor wound healing, so it's important to discuss these with the patient.
23 citations
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December 2021 in “Frontiers in Immunology” IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
13 citations
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February 2023 in “Pharmaceutics” Bioactive wound dressings can improve healing by promoting beneficial macrophage activity.
13 citations
,
July 2020 in “World journal of stem cells” Vitamin D and calcium are important for skin stem cell function and wound healing.
January 2026 in “Aging and Disease” Targeting mitochondria can improve skin health and slow aging.
August 2025 in “World Academy of Sciences Journal” Topical metformin shows promise for skin treatments but needs more testing for safety and effectiveness.
IL-1 signaling is crucial for hair follicle stem cell growth and wound healing.
24 citations
,
December 2016 in “Stem Cell Research & Therapy” P311 helps skin stem cells become myofibroblast-like cells, aiding wound healing.
25 citations
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June 2021 in “Developmental Cell” Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
22 citations
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February 2023 in “Heliyon” The hydrogel significantly speeds up wound healing and supports skin cell growth.
18 citations
,
June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
13 citations
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November 2021 in “Biomedicines” Plasma-activated liquid can kill harmful cells, speed up wound healing, and potentially treat cancer without damaging healthy cells.
3 citations
,
June 2023 in “MedComm” Stem cells and their exosomes show promise for repairing tissues and healing wounds when delivered effectively, but more research is needed on their tracking and optimal use.
1 citations
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June 2023 in “Cells” Exosomes could be a promising way to help repair skin and treat skin disorders.
March 2026 in “BMC Veterinary Research” Bovine amniotic membrane with propolis helped a cat's large skin wound heal quickly and fully.
December 2025 in “International Journal of Innovative Technologies in Social Science” Imbalanced skin microbiome can worsen skin conditions like acne and eczema.
March 2007 in “Journal of Plastic Reconstructive & Aesthetic Surgery” A new method was developed to create better skin models for healing and reconstruction.
154 citations
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November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
136 citations
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September 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.
49 citations
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March 2014 in “Journal of Investigative Dermatology” Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.
48 citations
,
April 2023 in “Aging Cell” Targeting cellular senescence may improve skin aging and disorders.
33 citations
,
January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
26 citations
,
January 2024 in “Gels” Nanoemulgels could effectively treat skin diseases and may replace or complement current therapies.
24 citations
,
August 2021 in “Biologics” Stem cell therapy shows promise in improving burn wound healing.
16 citations
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March 2025 in “International Journal of Molecular Sciences” Extracellular vesicles show promise in skin treatments but need more research and standardization.