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April 2023 in “Biomaterials advances” Gellan gum hydrogels help recreate the environment needed for hair growth cell function.
October 2024 in “SPIRE - Sciences Po Institutional REpository” Glypicans help hair follicle stem cells differentiate by interacting with specific receptors, influencing hair growth.
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May 2026 in “International Journal of Biological Macromolecules” The hydrogel with Poria cocos vesicles helps regrow hair in hair loss by activating specific cell signals.
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October 2023 in “Molecules” Plant-derived PDRN from ginseng roots effectively heals skin and improves its barrier.
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November 2017 in “Scientific Reports” Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.
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March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
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Polyglutamic acid is a valuable, sustainable ingredient for skincare and haircare products.
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April 2016 in “Journal of Investigative Dermatology” Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.
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Poly-D,L-lactic acid boosts hair growth in aged skin by activating hair follicle stem cells.
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April 2012 in “Science-business Exchange” Blocking a protein called prostaglandin D2 might help treat hair loss.
June 2026 in “Materials Today Bio” The study introduces a decellularized porcine amniotic membrane (dPAM) hydrogel, engineered using supercritical carbon dioxide, which effectively removes immunogenic components while preserving bioactive molecules crucial for skin regeneration. The hydrogel promotes angiogenesis, reduces pro-inflammatory responses, and enhances regenerative signaling in human follicle-derived dermal papilla cells, indicating its potential to influence hair follicle biology. In a UVB-induced skin inflammation murine model, the hydrogel demonstrated dual functionality by reducing early immune responses and promoting tissue repair. These findings suggest that dPAM hydrogel could serve as a bioactive platform for cutaneous repair and broader regenerative applications.
GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
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September 2019 in “Journal of Investigative Dermatology” Anti-Desmocollin 3 antibodies can cause pemphigus-like symptoms in mice.
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October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
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July 2014 in “Acta Crystallographica Section D-biological Crystallography” Mutations in the enzyme don't significantly change how it binds to its specific substances.