May 2024 in “Pigment International” Several treatments are effective for pigmentary disorders like vitiligo and melasma.
27 citations
,
January 1995 Melanin in black hair protects it from sun damage better than light-brown hair.
January 2022 in “Skin appendage disorders” Trichoscopy effectively visualizes scalp micropigmentation without invasive methods.
152 citations
,
December 2003 in “Micron” As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.
1 citations
,
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Increased PHGDH expression causes early melanin buildup in hair follicles.
17 citations
,
December 2013 in “Dermatologic Surgery” The treatment improved hair color in most vitiligo patients without major side effects.
December 2025 in “International Journal of Research in Dermatology” The Ayurvedic treatment safely and effectively restores natural hair color by increasing black hair and reducing grey hair.
June 2025 in “Albus Scientia” MC1R gene variations affect skin, hair color, UV sensitivity, and melanoma risk.
27 citations
,
March 2006 in “Dermatologic surgery” Medical tattooing is a widely accepted, easy, and permanent treatment with few side effects but carries an infection risk without proper sterilization.
March 2026 in “Portuguese Journal of Dermatology and Venereology” Avoid hair dye after microneedling to prevent scalp pigmentation.
15 citations
,
August 2014 in “Journal of dermatological science” Pueraria thunbergiana extract may help prevent hair from turning gray.
February 2009 in “Springer eBooks” Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.
20 citations
,
January 2015 in “Current problems in dermatology” Graying hair happens due to aging and might be delayed by new treatments.
17 citations
,
January 2015 in “Dermatology online journal” A patient's grey hair regained color during treatment with adalimumab.
15 citations
,
January 2017 in “Pigment International” Early hair graying is often inherited and influenced by genetics, environment, and lifestyle, but treatment options are limited.
15 citations
,
June 1986 in “Pediatric Dermatology” Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.
45 citations
,
August 1954 in “Experimental Biology and Medicine” Vitamin A penetrates guinea pig skin quickly in alcohol, affects skin thickness, but doesn't impact hair growth.
April 2023 in “International journal of dermatology and venereology” Dermoscopic features can help identify and differentiate types of pityriasis versicolor.
11 citations
,
January 2017 in “Oxidative medicine and cellular longevity” Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.
26 citations
,
February 2022 in “Journal of pineal research” Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
Acitretin treatment unexpectedly darkened a patient's gray hair.
August 2024 in “Journal of the American Academy of Dermatology” Nail color change might be an early sign of skin pigmentation from minocycline.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
28 citations
,
December 2011 in “Biocatalysis and biotransformation” PDI helps restore over-bleached hair's strength and structure by attaching special peptides.
April 2012 in “Development” Rac1 is crucial for normal hair structure and pigmentation.
31 citations
,
November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
12 citations
,
September 2020 in “Nanomaterials” The new drug delivery system improves vitiligo treatment by enhancing melanocyte activity and viability.
8 citations
,
August 2018 in “BMJ Case Reports” Pazopanib treatment caused rapid hair color loss, possibly indicating its effectiveness.
8 citations
,
July 2018 in “European Journal of Dermatology” A medication may help with hair growth in psoriasis, and a skin condition might be linked to a specific bacteria.
1 citations
,
April 2015 in “Neurology” Skin pigmentation increases in CRPS-affected areas and improves with symptom relief.