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GlossaryDermal Papilla Cell Proliferation

cells in hair follicle base multiply, promoting hair growth

Dermal Papilla Cell Proliferation refers to the process by which cells in the dermal papilla, a specialized structure at the base of hair follicles, multiply and grow. This cell activity is crucial for hair growth and regeneration, as these cells send signals that regulate the hair cycle and influence the formation of new hair shafts.

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research Injectable platelet rich fibrin facilitates hair follicle regeneration by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity

2 citations , October 2021 in “Experimental Cell Research”

Injectable platelet-rich fibrin helps hair growth by boosting key cell functions.

research Improvement of cell proliferation and antioxidant activity of silymarin in hair follicles dermal papillae isolated from the human scalp: Comparison with vitamin C effects

8 citations , January 2020 in “International Journal of Trichology”

Silymarin improves hair follicle health better than vitamin C by boosting cell growth and reducing oxidative stress.

research Triterpenes in the Ethanol Extract of Poria cocos Induce Dermal Papilla Cell Proliferation

3 citations , December 2019 in “International Journal of Pharmacology”

The ethanol extract of Poria cocos helps skin cells to grow.

research Effect of Orthosiphon stamineus plant extract on in vitro dermal papilla cell proliferation and ex vivo hair growth

1 citations , January 2017 in “Deleted Journal”

Orthosiphon stamineus extract can significantly boost hair growth and cell proliferation in hair loss patients.

research Teicoplanin alleviates androgenetic alopecia through inhibition of androgen receptor expression and enhancing dermal papilla cell proliferation

February 2026 in “European Journal of Pharmacology”

Teicoplanin may help treat hair loss by reducing androgen receptors and boosting hair cell growth.

Methanol Extract of Peach Kernel Induces Human Hair Follicle Dermal Papilla Cell Proliferation via the Extracellular Signal-Regulated Kinase Signaling Pathway

research Methanol Extract of Peach Kernel Induces Human Hair Follicle Dermal Papilla Cell Proliferation via the Extracellular Signal-Regulated Kinase Signaling Pathway

January 2024 in “Indian Journal of Pharmaceutical Sciences”

Peach kernel extract may promote hair growth by boosting cell growth in hair follicles.

research A study on the protective efficacy and cell proliferation of dermal papilla cells by spirulina extract

November 2022 in “Liberal Arts Innovation Center”

Spirulina extract may help protect the scalp and improve hair growth.

research Regulatory Effects of FGF9 on Dermal Papilla Cell Proliferation in Small-Tailed Han Sheep

May 2023 in “Genes”

FGF9 helps hair follicles grow in small-tailed Han sheep by affecting cell growth and certain signaling pathways.

research Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles

24 citations , January 2015 in “Annals of Dermatology”

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

research Argan (Argania Spinosa) press cake extract enhances cell proliferation and prevents oxidative stress and inflammation of human dermal papilla cells

14 citations , June 2021 in “Journal of dermatological science”

Argan press cake extract might help grow hair and protect hair cells from damage and inflammation.

Pantothenic Acid Promotes Dermal Papilla Cell Proliferation in Hair Follicles of American Minks via Inhibitor of DNA Binding 3/Notch Signaling Pathway

research Pantothenic acid promotes dermal papilla cell proliferation in hair follicles of American minks via inhibitor of DNA Binding 3/Notch signaling pathway

11 citations , April 2020 in “Life sciences”

Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.

research lncRNA2919 Suppresses Rabbit Dermal Papilla Cell Proliferation via trans-Regulatory Actions

4 citations , August 2022 in “Cells”

lncRNA2919 slows down rabbit hair growth by stopping cell growth and causing cell death.

research Ascorbigen Induces Dermal Papilla Cell Proliferation in Vitro , but Fails to Modulate Chemotherapy-Induced Alopecia in Vivo

2 citations , March 2013 in “Phytotherapy Research”

Ascorbigen increases hair cell growth in a lab setting but does not prevent hair loss from chemotherapy in mice.

research Studies on the effect of Betula platyphylla extract on human dermal papilla cell proliferation and its mechanism of action

December 2022 in “Journal of applied biological chemistry”

Betula platyphylla extract, particularly the H3-2 fraction, may help treat hair loss by promoting cell growth and inhibiting a hair loss-related enzyme.

research Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1

February 2023 in “International Journal of Molecular Sciences”

Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.

research Induction of Cell Proliferation and Cell Death in Human Follicle Dermal Papilla Cells by Zinc Chloride

2 citations , January 2019 in “Indian Journal of Pharmaceutical Sciences”

Zinc chloride can cause human scalp cells to multiply and die.

research Effect ofCinnamomum osmophloeumKanehira Leaf Aqueous Extract on Dermal Papilla Cell Proliferation and Hair Growth

20 citations , February 2018 in “Cell transplantation”

Cinnamomum osmophloeum leaf extract may help treat hair loss by promoting hair growth and increasing hair cell proliferation.

research (−)-Epigallocatechin-3-gallate promotes the dermal papilla cell proliferation and migration through the induction of VEGFA

January 2025 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research”

Green tea compound EGCG may help hair growth by boosting cell activity.

Cold Atmospheric Microwave Plasma Stimulates Dermal Papilla Cell Proliferation by Inducing Beta-Catenin Signaling

research Cold atmospheric microwave plasma (CAMP) stimulates dermal papilla cell proliferation by inducing β-catenin signaling

February 2023 in “Scientific Reports”

Cold Atmospheric Microwave Plasma (CAMP) helps hair cells grow and could potentially treat hair loss.

research Wheat Sprout Extract Stimulates Cell Proliferation via Phosphorylation of ERK and Akt in Human Dermal Papilla Cells

June 2017 in “Yakakoeji/Yaghag hoeji”

Wheat sprout extract boosts hair cell growth by activating specific proteins.

research Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation

71 citations , January 2019 in “International journal of biological sciences”

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Lactoferrin Promotes Hair Growth in Mice and Increases Dermal Papilla Cell Proliferation Through Erk/Akt and Wnt Signaling Pathways

research Lactoferrin promotes hair growth in mice and increases dermal papilla cell proliferation through Erk/Akt and Wnt signaling pathways

18 citations , April 2019 in “Archives of Dermatological Research”

Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.

research Heat-Killed Enterococcus faecalis EF-2001 Induces Human Dermal Papilla Cell Proliferation and Hair Regrowth in C57BL/6 Mice

4 citations , May 2022 in “International journal of molecular sciences”

Heat-killed Enterococcus faecalis EF-2001 may promote hair growth and transition hair follicles to the growth phase.

research Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation

4 citations , February 2019 in “BioMed Research International”

Ebastine may promote hair regrowth by increasing cell growth through the ERK pathway.

research The effects of extra cellular matrix and growth factors on dermal papilla cell proliferation

August 1994 in “Journal of dermatological science”

Different substances affect hair and skin cell growth in various ways.

Combination of Herbal Extracts and Platelet-Rich Plasma Induced Dermal Papilla Cell Proliferation: Involvement of ERK and Akt Pathways

research Combination of herbal extracts and platelet-rich plasma induced dermal papilla cell proliferation: involvement of ERK and Akt pathways

39 citations , June 2013 in “Journal of Cosmetic Dermatology”

Herbal extracts and platelet-rich plasma together may help increase hair growth by making certain cells grow more, through specific cell growth pathways.

Bacillus/Trapa Japonica Fruit Extract Ferment Filtrate Enhances Human Hair Follicle Dermal Papilla Cell Proliferation via the Akt/ERK/GSK-3β Signaling Pathway

research Bacillus/Trapa japonica Fruit Extract Ferment Filtrate enhances human hair follicle dermal papilla cell proliferation via the Akt/ERK/GSK-3β signaling pathway

10 citations , May 2019 in “BMC Complementary and Alternative Medicine”

The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.

Hair Growth-Promoting Mechanisms of Red Ginseng Extract Through Stimulating Dermal Papilla Cell Proliferation and Enhancing Skin Health

research Hair Growth-Promoting Mechanisms of Red Ginseng Extract through Stimulating Dermal Papilla Cell Proliferation and Enhancing Skin Health

3 citations , September 2021 in “Journal of Food Science and Nutrition”

Red Ginseng Extract helps hair grow and improves skin health by stimulating cell growth and enhancing the body's antioxidant defense system.

research Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway

2 citations , January 2022 in “Oxidative Medicine and Cellular Longevity”

Exosomes from dermal papilla cells help hair follicle stem cells grow and survive.

research Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation through the Chi-miR-214-3p/β-Catenin Axis in Cashmere Goats

7 citations , September 2022 in “International journal of molecular sciences”

The research found that the molecule lncRNA-H19 helps hair follicle cells grow by affecting certain cell pathways in cashmere goats.