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Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Finasteride and dutasteride reduce semen quality, with dutasteride having a stronger negative effect.

The procedure accurately measures 5-alpha-dihydrotestosterone in blood, useful for standard tests.

Astrotactin2 affects hair follicle orientation and skin cell polarity.

Small molecules can help turn skin cells into sweat gland-like cells for potential skin repair.

BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.

A new compound effectively inhibits human 5α-reductase 1.

Astrotactin-2 is cleaved in a specific way that helps understand its maturation.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

The models can help find better inhibitors for conditions like baldness and prostate disorders.

Sarolaner effectively treats generalized demodicosis in dogs without side effects.

Blocking Prostaglandin D₂ may help treat hair loss.

Dutasteride helps slow hair loss and boosts hair growth.

PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.

A new treatment for hair loss shows promise with fewer side effects.

Skin patting and iontophoresis with dutasteride gel improved hair growth in people with androgenetic alopecia.

A dog developed skin issues from too many steroids, but reducing steroids and using a specific treatment fixed the problems.

More men are using medication for benign prostatic hyperplasia, influenced by marketing and FDA approvals.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

A reliable method was created to measure dutasteride and related molecules in capsules.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Dutasteride improved both hair loss and acne in two young men.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

LX-38 is a safer drug option for treating prostate issues and hair loss without hormonal side effects.

The 0.05% dutasteride topical solution effectively promotes hair growth with fewer side effects than oral treatments.

Human dermal stem cells can become functional skin pigment cells.