12 citations
,
March 2023 in “The FASEB Journal” Platelet-rich plasma can improve erectile function in older individuals by reducing prostate enlargement.
Saw palmetto extract is effective and safe for treating lower urinary tract symptoms, working as well as certain medications, and works even better in severe cases.
235 citations
,
September 2004 in “The Journal of urology/The journal of urology” Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.
2 citations
,
January 2015 in “Journal of Investigative Dermatology” 1 citations
,
July 2022 in “Journal of Cataract and Refractive Surgery” Certain medications and conditions increase the risk of intraoperative floppy-iris syndrome.
Tadalafil may reduce the risk of major heart events and blood clots in men with urinary symptoms.
86 citations
,
March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
2 citations
,
February 2020 in “Journal of Investigative Surgery” Flutamide-induced hypospadias in rats slows down early wound healing.
September 2008 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Loss of Desmocollin 3 in mice causes skin blisters and hair loss.
53 citations
,
May 1996 in “The Journal of Clinical Endocrinology & Metabolism” Different mutations in the 5 alpha-reductase-2 gene were found in affected individuals in the Dominican Republic, suggesting no common ancestry.
1707 citations
,
December 2003 in “The New England Journal of Medicine” Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.
March 2025 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” Long-term use of dutasteride for hair loss may harm semen quality.
September 2024 in “Dermatology” Dutasteride works better than finasteride for hair loss and has mild, reversible side effects.
29 citations
,
April 2019 in “BMJ. British medical journal” Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
December 2021 in “Innovation in aging” Frailer men have a higher risk of worsening prostate problems and serious health events needing hospital care.
6 citations
,
August 2020 in “Frontiers in Pediatrics” Penile strangulation from hair can cause severe harm but can be treated if caught early.
22 citations
,
March 2018 in “International Ophthalmology” Taking tamsulosin or finasteride and being older increase the risk of floppy iris during cataract surgery.
71 citations
,
November 2012 in “Expert Opinion on Drug Safety” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
April 2016 in “The Journal of Sexual Medicine” 21 citations
,
January 1998 in “Urologia internationalis” All treatments helped with prostate symptoms, but the combination of dibenyline and finasteride worked best without extra side effects.
4 citations
,
October 2022 in “American journal of physiology. Heart and circulatory physiology” Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.
January 2016 in “Yanwaishang zhiye yanbing zazhi” Atropine and neosynephrine effectively prevent floppy iris syndrome during cataract surgery.
August 2009 in “Australian Prescriber” Dutasteride is approved to help manage prostate enlargement.
November 2005 in “PubMed” 34 citations
,
April 2006 in “PubMed” Tamsulosin is a cost-effective treatment for BPH symptoms.
72 citations
,
July 2002 in “Journal of Investigative Dermatology” Desmoglein 1 can partly make up for the loss of Desmoglein 3 in hair adhesion but not in mucous membranes.
6 citations
,
March 2005 in “The Journal of Urology”
April 2018 in “The Journal of Urology” Men with prediabetes have worse sexual health and a higher risk of severe erectile dysfunction.
10 citations
,
January 1995 in “Dermatology” Dermatologists should consider congenital syndromes like TRPS in young adults with early hair loss.
December 2025 in “Journal of the European Academy of Dermatology and Venereology”