Search

for
Search:

Sort by

Research

840-870 / 1000+ results

Synthesis of Novel Androstane-N-Cyclohexyl-17-Carboxamides and Their Effect on 5α-Reductase Isoform 2, Androgen Receptor, and Androgen-Dependent Glands

research Synthesis of novel andostane-N-cyclohexyl-17-carboxamides, and their effect on the 5α-reductase isoform 2, the androgen receptor, and androgen-dependent glands

November 2021 in “Pharmaceutical Sciences”

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

research Visual imaging of calcium ion distribution in acetone and tape stripping damaged canine epidermis.

June 2010 in “Journal of Veterinary Clinics”

The method visualized calcium ions in damaged canine skin, showing potential for studying skin recovery.

research 17-Oximino-5-androsten-3β-yl esters: synthesis, antiproliferative activity, acute toxicity, and effect on serum androgen level

7 citations , August 2010 in “Medicinal Chemistry Research”

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

research CUBIC Protocol Visualizes Protein Expression at Single Cell Resolution in Whole Mount Skin Preparations

6 citations , August 2016 in “Journal of Visualized Experiments”

The CUBIC protocol allows detailed 3D visualization of proteins in mouse skin biopsies.

$Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]$

research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt₂Cl₄(NH₃)₂{μ-HN=C(O)Bu^t}₂]

2 citations , November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials”

A new platinum complex was made and studied, which might help fight cancer better.

research Disposition and metabolism of finasteride in dogs.

5 citations , January 1997 in “PubMed”

research ダブルストロボレンジファインダの開発(特別講演)(画像センシングおよび一般)

January 2002 in “映像情報メディア学会技術報告”

Some prostate cancers have gene changes that may affect treatment with certain drugs.

research LC-MS/MS improves screening towards 21-hydroxylase deficiency

7 citations , December 2014 in “Gynecological Endocrinology”

LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.

The Efficacy and Safety of Creating a Rat Hypothyroidism Model Through Intramuscular Injection of 131 Iodine

research The Efficacy and Safety of Making Rat Hypothyroidism Model through Intramuscular Injection of 131Iodine

September 2025

Intramuscular injection of 131I is a safe and effective way to induce hypothyroidism in rats without harming muscle tissue.

Standardization, Validation, And Application Of A Rapid And Reliable HPLC-UV Method For The Determination Of Minoxidil In Hair Growth Products

research Standardization, Validation, and Application of a Rapid and Reliable HPLC-UV Method for the Determination of Minoxidil in Hair Growth Products

January 2025 in “Revista Vitae”

A new method reliably detects minoxidil in hair products, revealing some non-compliance with regulations.

research Micro-segmental analysis of the entry pathway and distribution of zolpidem in hair from different scalp regions after a single dose

May 2023 in “Frontiers in chemistry”

Zolpidem shows up in hair from the top back of the head after one dose and fades over time, suggesting it gets into hair through blood and sweat.

research Treatment of discoid lupus erythematosus scarring alopecia with deucravacitinib: A case report

3 citations , January 2025 in “SAGE Open Medical Case Reports”

Deucravacitinib helped regrow hair and reduce plaques in a woman with discoid lupus erythematosus without side effects.

research Improved two‐dimensional electrophoretic mapping of Japanese human hair proteins; application to curved and straight Japanese human hairs; and protein identification by MALDI MS and MS/MS quadrupole time‐of‐flight mass spectrometry

April 2020 in “International Journal of Cosmetic Science”

The study found that minor protein differences between curved and straight Japanese hair are unlikely to significantly affect hair structure.

research Fiber-Safe Extraction of Red Mordant Dyes from Hair Fibers

21 citations , January 1995 in “Journal of the American Institute for Conservation”

A new method extracts red dyes from wool without damaging it, although it slightly weakens the wool.

research RE: EFFECT OF THE DUAL 5α-REDUCTASE INHIBITOR DUTASTERIDE ON MARKERS OF TUMOR REGRESSION IN PROSTATE CANCER

3 citations , March 2005 in “The Journal of urology/The journal of urology”

Dutasteride may help shrink prostate cancer tumors.

research Detection of Iodine by Scanning Electron Microscopy(SEM) and Energy Dispersive Spectroscopy(EDS) Following Contact with an Iodine Releasing Coating

August 2000 in “Microscopy and Microanalysis”

The method successfully visualizes iodine in biological tissues.

research Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt

83 citations , October 2012 in “International Journal of Oncology”

Wedelolactone selectively kills prostate cancer cells without harming normal cells.

research Sex and estrous cycle influence diazepam effects on anxiety and memory: Possible role of progesterone

21 citations , May 2016 in “Progress in Neuro-Psychopharmacology and Biological Psychiatry”

Diazepam's effects on anxiety and memory differ between male and female rats due to hormonal influences.

research 51840 Efficacy of the Oral JAK1/JAK2 Inhibitor Deuruxolitinib in Adult Patients with Moderate to Severe Alopecia Areata: Pooled Results from the Multinational Double-Blind, Placebo-Controlled THRIVE-AA1 and THRIVE-AA2 Phase 3 Trials

2 citations , September 2024 in “Journal of the American Academy of Dermatology”

Deuruxolitinib significantly helps regrow scalp hair in adults with moderate to severe alopecia areata.

research Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors

1 citations , October 2020 in “Current Drug Discovery Technologies”

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

Incomplete Recovery of Erectile Function in Rats After Discontinuation of Dual 5-Alpha Reductase Inhibitor Therapy

research Incomplete Recovery of Erectile Function in Rat after Discontinuation of Dual 5‐Alpha Reductase Inhibitor Therapy

29 citations , July 2012 in “The Journal of Sexual Medicine”

Rats had lasting erectile problems after stopping a certain medication.

research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor

408 citations , May 2004 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

research Neurosteroids Involved in Regulating Inhibition in the Inferior Colliculus

19 citations , September 2006 in “Journal of Neurophysiology”

Neurosteroids help balance brain signals when certain inhibitions are reduced.

Sensitive Quantitative In Vivo Assay for Evaluating the Effects of Biomolecules on Hair Growth and Coloring Using Direct Microinjections into Mouse Whisker Follicles

research Sensitive Quantitative In Vivo Assay for Evaluating the Effects of Biomolecules on Hair Growth and Coloring Using Direct Microinjections into Mouse Whisker Follicles

July 2023 in “Biomolecules”

The new "whisker follicle microinjection assay" can test how different biomolecules affect hair growth and color.

research SUN-376 Isolated DHEA-S Production by an Adrenal Neoplasm: Clinical, Biochemical, and Pathologic Findings

April 2019 in “Journal of the Endocrine Society”

A rare adrenal tumor in a woman only made DHEA-S, causing hair thinning, and was removed, fixing the hormone level.

research Determination of some sex hormones in health supplements by liquid chromatography with tandem mass spectrometry

December 2023 in “Kiểm nghiệm và An toàn thực phẩm/Kiểm nghiệm và An toàn thực phẩm (online)”

The method detected sex hormones in some health supplements, with one containing banned testosterone.

research Fully automated chip-based nanoelectrospray ionization-mass spectrometry as an effective tool for rapid and high-throughput screening of 5α-reductase inhibitors

7 citations , February 2020 in “Analytical and Bioanalytical Chemistry”

Diphlorethohydroxycarmalol, Isolated from Ishige Okamurae, Increases Prostaglandin E2 through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes

research Diphlorethohydroxycarmalol, Isolated from Ishige okamurae, Increases Prostaglandin E₂through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes

9 citations , November 2012 in “Biomolecules & therapeutics”

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

research Experimental Production of Cutaneous Calcinosis and Sclerosis with Dihydrotachysterol (AT-10) 1

12 citations , July 1957 in “Journal of Investigative Dermatology”

Giving dihydrotachysterol to mother rats caused skin hardening and bone issues in their babies through milk.

research Lead-revealed lipid organization in human hair

35 citations , February 2003 in “Biochimica et Biophysica Acta (BBA) - General Subjects”

Lead can help reveal and organize lipids in human hair.

← Previous page Next page →