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540-570 / 1000+ resultsresearch Effect of a novel steroid (PM-9) on the inhibition of 5α-reductase present in Penicillium crustosum broths
PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.
research Forsythiae Fructus: A Review on its Phytochemistry, Quality Control, Pharmacology and Pharmacokinetics
Forsythiae Fructus has anti-inflammatory, antibacterial, and antiviral properties, with differences between unripe and ripe forms important for clinical use.
research THE TREATMENT OF HIRSUTISM WITH A COMBINATION OF DESOGESTREL AND ETHINYL OESTRADIOL
A combination of desogestrel and ethinyl oestradiol effectively reduces hair growth in hirsute women.
research Anti-Inflammatory and Antifungal Activities of Wood Essential Oil from Juniperus morrisonicola Hayata
Juniperus morrisonicola wood essential oil has strong anti-inflammatory and antifungal properties.
research Minoxidil topical foam: A new kid on the block
Minoxidil topical foam is a better, less irritating treatment for hair loss.
research Unlocking Dithranol’s Potential: Advanced Drug Delivery Systems for Improved Pharmacokinetics
Advanced delivery systems can make dithranol more effective and less irritating for treating psoriasis.
research Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABAAReceptor Function and Seizure Susceptibility
Stress increases neurosteroids that help prevent seizures.
research Early COVID-19 Therapy with Azithromycin Plus Nitazoxanide, Ivermectin or Hydroxychloroquine in Outpatient Settings Significantly Reduced Symptoms Compared to Known Outcomes in Untreated Patients.
Early treatment with azithromycin and other drugs reduced COVID-19 symptoms and complications.
research Recent advances in the molecular mechanisms causing primary generalized glucocorticoid resistance
Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
research Finasteride plus doxazosin combination tops in BPH
research Traditional Uses and Pharmacologically Active Constituents of Dendrobium Plants for Dermatological Disorders: A Review
Dendrobium plants have compounds useful for treating skin issues and developing new drugs and cosmetics.
research Germacrone and sesquiterpene-enriched extracts from Curcuma aeruginosa Roxb. increase skin penetration of minoxidil, a hair growth promoter
Certain extracts from Curcuma aeruginosa Roxb. and germacrone can boost the skin's absorption of minoxidil, a hair growth promoter, making it more effective.
research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An in Silico and in Vitro Study
Five preservatives may disrupt hormone function and need more health and environmental risk assessment.
research Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
research Repurposing existing drugs for the treatment ofCOVID-19/SARS-CoV-2: A review of pharmacological effects and mechanism of action
Metformin may help mild COVID-19 cases, while Oseltamivir, Tamoxifen, and Dexamethasone are suggested for severe cases.
research Solubilities of Flutamide, Dutasteride, and Finasteride as Antiandrogenic Agents, in Supercritical Carbon Dioxide: Measurement and Correlation
Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.
research Glucocorticoid corticosteroids for Duchenne muscular dystrophy
Glucocorticoid corticosteroids improve muscle strength in Duchenne muscular dystrophy but can cause side effects.
research DEVELOPING AND VALIDATING AN HPLC METHOD TO QUANTIFY SIMULTANEOUSLY DUTASTERIDE AND THEIR RELATED MOLECULES (DUTASTERIDE ACID, 2,5 BIS- (TRI FLUORO METHYL)-ANILINE AND DUTASTERIDE 17 α-EPIMER) IN CAPSULES
A reliable method was created to measure dutasteride and related molecules in capsules.
research A Concise Review on Biological Activity of Tridax procumbens Linn
Tridax procumbens has medicinal properties like healing, pain relief, and infection control.
research Effects of Solventson Spherical Crystals of Minoxidil
Different solvents affect minoxidil crystal shapes, improving flowability and revealing a unique butterfly-shaped crystal.
research UK High Court Revokes Escitalopram UK Patent; Validity of Second Medical use Claims Based on Dosage Regimes in the UK; Stay of Proceedings in the UK Courts Pending EPO Opposition Proceedings
The UK High Court revoked Lundbeck's patent for Escitalopram, and second medical use claims based on dosage were not considered novel.
research Trichotillomania as a Manifestation of Dementia
Trichotillomania in dementia may be better treated with dopamine blockers like quetiapine than with SSRIs.
research Preliminary Toxicity Profile of Arotinoids SMR-2 and SMR-6 in Male B6D2F1 Mice
SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe symptoms and organ damage in mice.
research HPTLC assay of nicotine and cotinine in biological samples
A new method effectively measures nicotine and cotinine in blood and urine for forensic analysis.
research Review of Fluconazole Properties and Analytical Methods for Its Determination
Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.
research An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 5-alpha-dihydrotestosterone in human serum and plasma
The procedure accurately measures 5-alpha-dihydrotestosterone in blood, useful for standard tests.
research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
research A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest
Deep eutectic solvents are eco-friendly and effective for extracting useful pharmaceutical compounds.