research Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts
Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.
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780-810 / 1000+ results research Breast cancer in a transgender man
Transgender men need personalized cancer care and continued testosterone therapy for well-being.
research Activity of steroid 4 and derivatives 4a–4f as inhibitors of the enzyme 5α-reductase 1
Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
research Paradoxical Nonscarring Alopecia Following Mesotherapy with Dutasteride: A Case Series
Dutasteride mesotherapy can cause hair loss in some people.
research Association between finasteride with subjective memory deficits: a study from the NHANES and FAERS databases
Finasteride use is linked to a higher risk of memory problems.
research Endocrinology
The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
research Connarus semidecandrus Jack Exerts Anti-Alopecia Effects by Targeting 5α-Reductase Activity and an Intrinsic Apoptotic Pathway
Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
research An exploratory analysis of 5‐alpha reductase inhibitors and risk of opioid use disorder among male Medicare beneficiaries receiving prescription opioid medications
Using 5-alpha reductase inhibitors may lower the risk of opioid addiction in men taking opioids.
research Association of Androgenetic Alopecia with Metabolic Syndrome
People with androgenetic alopecia are more likely to have metabolic syndrome.
research Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5α-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects
Pumpkin Seed Oil in niosomes may help treat hair loss and improve hair growth.
research Evaluation of the safety and efficacy of concentrated growth factors for hair growth promotion in androgenetic alopecia patients: A retrospective single‐centre, single‐arm study
CGF injections may safely and effectively promote hair growth in androgenetic alopecia patients.
research Whole-Genome Resequencing Reveals Selection Signal Related to Sheep Wool Fineness
Genes linked to wool fineness in sheep have been identified.
research Evaluating the diagnostic accuracy of androgen measurement in polycystic ovary syndrome: a systematic review and diagnostic meta-analysis to inform evidence-based guidelines
Androgen measurement helps diagnose PCOS, but accuracy varies, needing standard methods.
research The Pathogenesis of Oxidative Stress in Androgenetic Alopecia
Oxidative stress damages hair follicles and worsens hair loss in androgenetic alopecia.
research Early breast development in girls after prenatal exposure to non‐persistent pesticides
Prenatal pesticide exposure may cause earlier breast development in girls.
research Copper-quercetin complexes: methods of study, relevance to cell death pathways, therapeutic applications
Copper-quercetin complexes could be effective in treating cancer, infections, and promoting bone healing.
research Unveiling a Shared Precursor Condition for Acne Keloidalis Nuchae and Primary Cicatricial Alopecias
A condition with certain scalp changes may come before acne keloidalis nuchae and other similar hair loss disorders.
research Insulin Resistance, Metabolic Syndrome, and Inflammatory Skin Disease
Improving diet and lifestyle can help manage skin conditions linked to insulin resistance and inflammation.
research Androgenetic Alopecia: A Review
Androgenetic alopecia is a common hair loss condition influenced by various factors and linked to psychosocial and cardiovascular issues.
research The Role of Probiotics and Synbiotics on Hirsutism
Probiotics and synbiotics might help manage hirsutism by improving insulin resistance.
research Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production
Omega-6 fats in certain cells boost male hormone production.
research Stimuli-responsive nanoformulations for CRISPR-Cas9 genome editing
Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
research Simultaneous Determination of Selected Steroids with Neuroactive Effects in Human Serum by Ultrahigh-Performance Liquid Chromatography–Tandem Mass Spectrometry
A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.
research Diagnosis, Pathogenesis and Management of Polycystic Ovary Syndrome
Lifestyle changes and insulin-sensitizing drugs are effective for managing PCOS.
research RETRACTED: Genetic association between asthma and alopecia areata: A two‐sample Mendelian randomization study
Asthma may increase the risk of alopecia areata.
research Causal Effects of Lipids-Related Metabolites on Androgenic Alopecia: A Mendelian Randomization Study
Certain fats in the blood are linked to an increased risk of male pattern baldness.
research 5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes
Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.
research Association between male pattern baldness and testicular germ cell tumor: a meta-analysis
Baldness may lower the risk of testicular cancer.
research Clinical and hormonal effects of the 5 alpha-reductase inhibitor finasteride in idiopathic hirsutism.
Finasteride reduces hair growth and is safe for women with excessive hair.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility1
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.