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April 2018 in “Journal of Investigative Dermatology” PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.
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October 1988 in “Clinics in dermatology” The document concludes that understanding how cells in the hair follicle grow and change is important for regulating hair growth.
March 2024 in “Advanced healthcare materials/Advanced Healthcare Materials” Scientists developed a new way to create skin-like structures from stem cells using a special 3D gel and a device that improves cell organization and increases hair growth.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Elf5 is important for skin stem cell growth and could help treat skin and hair problems.
October 2021 in “Journal of Investigative Dermatology” The study concludes that as skin matures from infancy to childhood, there are major changes in cell differentiation, stemness, and growth, leading to a stronger skin barrier in older children.
April 2017 in “Journal of dermatological science” Young mice's hair follicle stem cells are best for turning into heart muscle cells.
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March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
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May 2001 in “Proceedings of the National Academy of Sciences” Overexpression of COX-2 in mice skin causes abnormal skin and hair development.
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September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
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June 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” PAI-2 helps in the maturation and protection of hair and nail cells.
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February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Plet-1 protein helps hair follicle cells move and stick to tissues.
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December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
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October 2024 in “Cells” Autophagy is essential for proper skin cell development and function.
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January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
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May 2021 in “International journal of molecular sciences” Stem cells from hair follicles in a special gel show strong potential for bone regeneration.
December 2025 in “The Journal of Cell Biology” Keratin 15 helps maintain skin cell growth and repair.
January 2025 in “PLoS ONE” Elf5 controls skin cell growth and development, making it a potential target for skin treatments.
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April 2008 in “Current opinion in cell biology” Notch signalling helps skin cells differentiate and prevents tumors.
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March 2013 in “Expert opinion on biological therapy” Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
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September 2007 in “Cell Cycle” Stem cells in hair follicles can become various cell types, including neurons.
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January 2023 in “Cell Transplantation” Nanofat with stem cells is promising for treating hair loss, scars, and skin rejuvenation.
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January 2016 in “Stem Cells International” Adipose-derived stem cells are promising for tissue and organ repair due to their easy access and versatility.
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April 2014 in “PloS one” Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.
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May 2002 in “Journal of Investigative Dermatology” A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
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June 2018 in “Frontiers in immunology” Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
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January 2013 in “BMC Dermatology” TGFβ signaling prevents sebaceous gland cells from producing fats.