research Solubility of Foreign Molecules in Stratum Corneum Brick and Mortar Structure
Solubility in skin changes with hydration, affecting chemical absorption.
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210-240 / 1000+ resultsresearch Diffuse Alopecia Areata
Diffuse alopecia areata causes widespread hair thinning due to an autoimmune response.
research Water distribution in human hair microstructure elucidated by spin contrast variation small-angle neutron scattering
The technique showed that human hair has two main parts, with 68% being rigid and the rest flexible, and water swelling affects its structure.
research Experimental, molecular docking investigations and bioavailability study on the inclusion complexes of finasteride and cyclodextrins
Combining finasteride with dimethyl-β-cyclodextrin improves its absorption and bioavailability.
research Potassium Channel Conductance as a Control Mechanism in Hair Follicles.
research Electroosmotic pore transport in human skin.
research OVERCOMING THE BARRIERS TO EFFECTIVE DRUG DELIVERY TO THE BRAIN
New methods are being developed to improve drug delivery to the brain.
research Fluid Loss Through Epidermis of the Rat and Factors Affecting It.
Fluid loss through rat skin is minimal when inactive but increases with skin activity and hair growth.
research Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching (FRAP) Is an Integrated Measure of Receptor Function
Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.
research Low sex-hormone binding globulin levels in young women with diffuse hair loss
Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.
research Thyroid Functions in Patients with Diffuse Hair Loss
Diffuse hair loss in women is often linked to thyroid problems.
research In vivo Quantification of the Effects of Radiation and Presence of Hair Follicle Pores on the Proliferation of Fibroblasts in an Acellular Human Dermis in a Dorsal Skinfold Chamber: Relevance for Tissue Reconstruction following Neoadjuvant Therapy
Hair follicle pores help cell survival and growth, even after radiation.
research The Novel Excipient, Dodecyl-2-N, N-dimethylaminopropionate Hydrochloride (DDAIP-HCl) Improves the Flux of Minoxidil in Human Skin
DDAIP-HCl significantly increases minoxidil absorption into the skin.
research Advancements in Therapeutic Deep Eutectic Solvents as Multifunctional Transdermal Delivery Systems
TheDES improve drug delivery through the skin but need more safety checks.
research Fundamental studies on the interaction between moisture and textiles. Part X. Moisture sorption properties of wool and hair fibers.
Wool and hair fibers absorb moisture similarly due to their keratin structure, with the amount of non-crystalline areas affecting the moisture uptake.
research Nanocarrier Systems for Transdermal Drug Delivery
Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
research Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles
Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
research Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs
Nanoporous silica entrapped lipid-drug complexes significantly improve the solubility and absorption of drugs that don't dissolve well in water.
research The preparation of high minoxidil loaded transfersomes and its gel for effective topical treatment of alopecia
The new minoxidil gel improves hair growth and reduces skin irritation.
research Follicular and percutaneous penetration pathways of topically applied minoxidil foam
Minoxidil foam enters hair follicles and skin for hair growth.
research Dual‐flow‐RootChip reveals local adaptations of roots towards environmental asymmetry at the physiological and genetic levels
Roots adapt to uneven environments by changing growth and gene expression.
research Diffuse Alopecias
The paper concludes that detailed patient history, skin exams, and lab tests are crucial for diagnosing and treating hair loss from diffuse alopecia.
research Development and Skin Penetration Pathway Evaluation Using Confocal Laser Scanning Microscopy of Microemulsions for Dermal Delivery Enhancement of Finasteride
Finasteride-loaded microemulsions can effectively enhance skin delivery for treating hair loss.
research Percutaneous Absorption of Minoxidil in Man
Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.
research Differential expression and functionality of ATP-binding cassette transporters in the human hair follicle
Certain transporters are found in human hair follicles and may affect hair growth and loss.
research Enhancement of Dermal Delivery of Finasteride Using MicroemulsionSystems
Microemulsions can improve skin delivery of finasteride.
research Differentiation capacity of stromal fibroblast-like cells from human bone marrow, adipose tissue, hair follicle dermal papilla and derma
research Comparison of Epidermal Growth Factor Binding and Receptor Distribution in Normal Human Epidermis and Epidermal Appendages
research Percutaneous penetration of hair dyes
Hair dyes penetrate the scalp very minimally, less than 1%.
research Investigation of transfollicular caffeine penetration using microdialysis on ex vivo porcine ear skin
Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.