research Synthesis and bioactivity of new Finasteride conjugate
New Finasteride conjugate improves prostate treatment and vital signs in rats.
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research Facile One-Pot Synthesis of Substituted Hydantoins from Carbamates
Scientists in India found a safer and efficient way to make a type of medicine called hydantoins from carbamates, which also worked well in making the seizure medicine, Ethotoin.
research Solid-state cultivation of multiple industrial strains of koji mold on different Thai unpolished rice cultivars: biotransformation of phenolic compounds and their effects on antioxidant activity
Koji mold on unpolished Thai-colored rice boosts antioxidant activity more than on other rice types.
research Inflammasome Proteins as Biomarkers of Injury and Disease
Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.
research Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review
Tripeptides help heal wounds and regenerate skin by speeding up tissue repair and reducing inflammation.
research Secreted subtilisin Sub3 from Microsporum canis is required for adherence to but not for invasion of the epidermis
Sub3 is essential for fungus adherence but not for skin invasion.
research Candidate genes of SARS-CoV-2 gender susceptibility
Men are more affected by COVID-19 due to differences in immune responses and protein expression.
research Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Polycystic ovary syndrome and risks for COVID-19 infection: A comprehensive review
Women with PCOS have a higher risk of severe COVID-19 due to related health issues.
research Industry Report
The regenerative medicine industry saw business growth with new partnerships, clinical trials, and financial investments.
research Peptide-Based Approaches for Pain Relief and Healing in Wounds
Topical peptides may offer safer, effective pain relief and healing for wounds.
research Recent Advances in Peptide Drug Discovery: Novel Strategies and Targeted Protein Degradation
Peptide drugs now target hard-to-reach proteins more effectively and specifically.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research Deep Insight of Design, Mechanism, and Cancer Theranostic Strategy of Nanozymes
Nanozymes show promise for effective and safe cancer treatment.
research Absorption sites of orally administered drugs in the small intestine
Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.
research Differential gene expression analysis between anagen and telogen of Capra hircus skin based on the de novo assembled transcriptome sequence
Signaling pathways are crucial for hair growth in goats.
research Current Perspectives on the Physiological Activities of Fermented Soybean-Derived Cheonggukjang
Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.
research Immunolocalization of a Histidine-Rich Epidermal Differentiation Protein in the Chicken Supports the Hypothesis of an Evolutionary Developmental Link between the Embryonic Subperiderm and Feather Barbs and Barbules
A specific protein in chicken embryos links early skin layers to feather development.
research Innovations in Skin and Soft Tissue Aging—A Systematic Literature Review and Market Analysis of Therapeutics and Associated Outcomes
Stem cell therapies show the most promise for anti-aging benefits.
research Clinical Study to Evaluate the Efficacy and Safety of a Hair Serum Product in Healthy Adult Male and Female Volunteers with Hair Fall
The hair serum significantly improved hair growth and reduced hair fall without causing any skin issues.
research Molecular modeling of hair keratin/peptide complex: Using MM‐PBSA calculations to describe experimental binding results
Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.
research Biological effects of human placental extracts - variations in manufacturing methods and compositions
Placental extracts have antioxidant, anti-inflammatory, and immune-boosting effects, but their exact workings are unclear.
research The action of a cosmetic hair treatment on follicle function
The hair treatment made hair grow faster and thicker and strengthened the hair roots.
research Effect of ethanol extract of Zapoteca portoricensis stem on liver, kidney and prostatic biomarkers of testosterone-induced benign prostate hyperplasia (BPH) in male albino rats
Zapoteca portoricensis extract may help protect against prostate issues and support liver and kidney health in rats.
research The effects and mechanisms of collagen peptides for alleviating skin ageing
Collagen peptides may help reduce skin aging by improving elasticity and hydration.
research Woodhouse-Sakati syndrome: genotype–phenotype review and case of intra-familial heterogeneity
Woodhouse-Sakati syndrome shows varied symptoms and genetic differences within families.
research TON1 recruiting motif 21 positively regulates the flavonoid metabolic pathway at the translational level in Arabidopsis thaliana
TRM21 helps control flavonoid production and root hair growth in Arabidopsis thaliana.
research Design, Synthesis, and Preclinical Evaluation of Prostate-Specific Membrane Antigen Targeted 99mTc-Radioimaging Agents
Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research Nanozymes expanding the boundaries of biocatalysis
Nanozymes greatly improve biocatalysis by being stable, efficient, and versatile.