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Did you mean DNA fragmentation?

GlossaryDNA fragmentation

breaking of DNA strands into smaller pieces

DNA fragmentation refers to the breaking of DNA strands into smaller pieces. This can occur naturally during processes like apoptosis (programmed cell death) or can be induced by external factors such as radiation or certain chemicals. In a clinical or research setting, measuring DNA fragmentation can be important for understanding cell health, diagnosing diseases, or assessing the quality of sperm in fertility studies.

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Selective Induction of Apoptosis in the Hamster Flank Sebaceous Gland Organ by a Topical Liposome 5-Alpha-Reductase Inhibitor: A Treatment Strategy for Acne

research Selective induction of apoptosis in the hamster flank sebaceous gland organ by a topical liposome 5-α-reductase inhibitor: A treatment strategy for acne

8 citations , February 2010 in “Journal of Dermatology”

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

research Apoptotic cell death in canine hair follicle.

5 citations , January 2005 in “PubMed”

Apoptosis is important in the hair cycle of dogs.

research Recent advances in understanding and managing male infertility

104 citations , May 2019 in “F1000Research”

Losing weight, fixing varicoceles, and using advanced sperm selection methods improve male infertility treatment outcomes.

research Forensic DNA phenotyping: the need for proportionate regulation and judicial clarity in law enforcement

March 2026 in “Egyptian Journal of Forensic Sciences”

Unified regulations and ethical guidelines are needed for fair use of forensic DNA phenotyping.

research A Simple Method to Extract DNA from Hair Shafts Using Enzymatic Laundry Powder

8 citations , July 2013 in “PLoS ONE”

DNA can be quickly and effectively extracted from hair using laundry powder.

research Tracking research trends and hotspots in sperm DNA fragmentation testing for the evaluation of male infertility: a scientometric analysis

48 citations , December 2019 in “Reproductive Biology and Endocrinology”

More research is needed to confirm sperm DNA fragmentation as a reliable tool for diagnosing male infertility.

research 287 Mackerel fermented fish oil suppresses human keratinocyte damage caused by ultraviolet B radiation

September 2017 in “Journal of Investigative Dermatology”

Mackerel fermented fish oil protects skin cells from damage by UVB light.

research Apoptosis in human skin development: Morphogenesis, periderm, and stem cells

253 citations , March 1994 in “Developmental dynamics”

Apoptosis is essential for human skin development and forming a functional epidermis.

research Male reproductive health after 3 months from SARS-CoV-2 infection: a multicentric study

46 citations , August 2022 in “Journal of Endocrinological Investigation”

COVID-19 temporarily affects male reproductive health, but sperm and testosterone levels generally return to normal after three months.

research Effects of High-dose Radioactive Iodine Therapy on Hormonal Profiles and Sperm Quality in Thyroidectomy Patients

February 2026 in “Molecular Imaging and Radionuclide Therapy”

High-dose radioactive iodine therapy does not harm fertility in thyroidectomy patients.

research PD05-10 COMPARATIVE EFFECTS OF FINASTERIDE AND DUTASTERIDE ON SEMEN PARAMETERS IN YOUNG MEN WITH ANDROGENIC ALOPECIA: A RANDOMIZED CONTROLLED STUDY

April 2026 in “The Journal of Urology”

Finasteride and dutasteride reduce semen quality, with dutasteride having a stronger negative effect.

research Inhibition of 5-Alpha Reductase Attenuates Cardiac Oxidative Damage in Obese and Aging Male Rats via the Enhancement of Antioxidants and the p53 Protein Suppression

September 2024 in “Chemico-Biological Interactions”

Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

research Copper-quercetin complexes: methods of study, relevance to cell death pathways, therapeutic applications

2 citations , April 2025 in “Biomedicine & Pharmacotherapy”

Copper-quercetin complexes could be effective in treating cancer, infections, and promoting bone healing.

research Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?

February 2026 in “Andrology”

Post-orchidectomy semen has better DNA integrity for fertility treatments.

research Advantages of Incomplete Digestion in Human Hair Shaft Proteomics, a Focus on Cuticular Keratins

June 2025 in “Rapid Communications in Mass Spectrometry”

The new method improves protein extraction and analysis in hair, aiding biomedical and forensic work.

research Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia

28 citations , December 2001 in “European Journal of Pharmacology”

M50054 may help treat hepatitis and hair loss from chemotherapy.

research Forensic skeletal and molecular anthropology face to face: Combining expertise for identification of human remains

4 citations , July 2025 in “Annals of the New York Academy of Sciences”

Combining skeletal and molecular anthropology improves identifying human remains.

research The Mitochondrial Blueprint of Skin Aging: From Damage Signals to Dermatologic Interventions

January 2026 in “Aging and Disease”

Targeting mitochondria can improve skin health and slow aging.

research Single-strand DNA breaks in human hair root cells exposed to mobile phone radiation

37 citations , March 2012 in “International Journal of Radiation Biology”

Mobile phone radiation can cause DNA damage in human hair root cells.

research Proliferation, DNA repair and apoptosis in androgenetic alopecia

19 citations , August 2008 in “Journal of The European Academy of Dermatology and Venereology”

Bald areas have lower cell growth, more DNA damage, and increased cell death.

research Araliadiol Protects Human Keratinocytes From Oxidative Stress, DNA Damage, and Apoptosis via Activation of Antioxidant Signaling

January 2026 in “Frontiers in Bioscience-Landmark”

Araliadiol protects skin cells from damage by boosting antioxidant defenses.

Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia

research Evidence of increased DNA methylation of the androgen receptor gene in occipital hair follicles from men with androgenetic alopecia

24 citations , March 2011 in “British Journal of Dermatology”

Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.

research M5 isolation method preserves higher trichogenic identity and proliferative capacity of human dermal papilla cells

June 2026 in “Applied Biological Chemistry”

The M5 method is best for isolating cells that help hair growth.

Transient Mitochondrial DNA Double Strand Breaks in Mice Cause Accelerated Aging Phenotypes in a ROS-Dependent but p53/p21-Independent Manner

research Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner

42 citations , December 2016 in “Cell Death & Differentiation”

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

research Biological effects of human placental extracts - variations in manufacturing methods and compositions

1 citations , December 2025 in “Frontiers in Pharmacology”

Placental extracts have antioxidant, anti-inflammatory, and immune-boosting effects, but their exact workings are unclear.

Generating Detailed Intercellular Communication Patterns in Psoriasis at the Single-Cell Level Using Social Networking, Pattern Recognition, and Manifold Learning Methods to Optimize Treatment Strategies

research Generating detailed intercellular communication patterns in psoriasis at the single-cell level using social networking, pattern recognition, and manifold learning methods to optimize treatment strategies

January 2024 in “Aging”

New insights into cell communication in psoriasis suggest innovative drug treatments.

research Evaluation of apoptosis regulatory markers in androgenetic alopecia

6 citations , December 2010 in “Journal of Cosmetic Dermatology”

Apoptosis may contribute to hair loss in androgenetic alopecia.

Comparison of the Effectiveness of Different Snare Types for Collecting and Retaining Hair from Eurasian Lynx (Lynx lynx)

research Comparison of the effectivity of different snare types for collecting and retaining hair from Eurasian Lynx (Lynx lynx)

4 citations , March 2012 in “European journal of wildlife research”

Wire brush snares are best for collecting Eurasian Lynx hair for DNA analysis.

research Evaluation of hydro-alcoholic extract of Eclipta alba for its anticancer potential: An in vitro study

50 citations , May 2011 in “Journal of Ethnopharmacology”

Eclipta alba extract shows potential as an anticancer agent by inhibiting cancer cell growth and promoting cell death.

Risk Factors for Prostate Cancer: A Case-Control Study Investigating Key Exposures and Gene Interactions

research Risk factors for prostate cancer: a case-control study investigating selected key exposures and their interactions with predisposition genes

December 2010 in “Jurnal Natural (Faculty of Mathematics and Natural Science, Syiah Kuala University)”

Age, race, family history, and certain genetic factors increase prostate cancer risk.