April 2017 in “Journal of dermatological science” Young mice's hair follicle stem cells are best for turning into heart muscle cells.
3 citations
,
October 2024 in “Frontiers in Medicine” Sun-exposed skin shows different cell activity and gene expression, suggesting targets to prevent skin aging and cancer.
20 citations
,
April 2002 in “PubMed” Mini rats have thinner skin, more fat, and different hair cycles than Wistar rats due to lower growth hormone levels.
3 citations
,
July 2017 in “Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model” Mouse hair follicle stem cells have a flexible chromatin state that supports skin health and hair growth.
2 citations
,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” miR-29 is a key factor that accelerates aging.
5 citations
,
March 2009 in “Skin Pharmacology and Physiology” DNA flow cytometry effectively evaluates how different conditions affect hair growth cell activity.
5 citations
,
July 2022 in “Journal of Investigative Dermatology” Aged skin heals slower due to more inflammation and disrupted cell communication.
5 citations
,
June 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Putting thymidine dinucleotide on newborn mice's skin can delay and reduce skin cancer.
October 2020 in “Research Square (Research Square)” Aging-related changes in hair follicle stem cells can be partially reversed with a specific treatment.
153 citations
,
June 2015 in “GenomeBiology.com” The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.
January 2023 in “Türkiye klinikleri adli tıp ve adli bilimler dergisi” DNA markers can help predict male pattern baldness, useful in criminal and missing person cases.
Moles may stop growing because of cell cooperation, not just because of aging cells.
33 citations
,
April 2005 in “British Journal of Dermatology” Aging alone barely affects the number of hair follicles, meaning hair loss is minimal without other conditions like androgenetic alopecia.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists created a detailed map of gene activity in different parts of human hair follicles.
13 citations
,
July 2020 in “Stem Cell Research & Therapy” Young donor, early passage stem cells have the highest stemness.
75 citations
,
June 2007 in “Journal of Biological Chemistry” MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.
October 1997 in “Dermatologic Clinics” The aging population's demand for aesthetic medicine is increasing due to longer life expectancy and societal factors.
July 2007 in “Cancer biology & therapy” Removing a key gene in mice leads to premature aging and loss of stem cells.
39 citations
,
August 2022 in “Cell Death and Disease” DA-MeHA hydrogel effectively aids stem cell-based skin regeneration.
RNase L hinders hair follicle regeneration by altering immune signals.
15 citations
,
December 2014 in “PLoS ONE” A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
4 citations
,
August 2018 in “Journal of cellular biochemistry” Acid inside cells speeds up aging and turns on aging signs in mice.
2 citations
,
February 2021 in “Developmental Cell” Middle-aged skin shows aging signs, and quercetin might help delay them.
September 2022 in “PubMed” Collagen type XVII α1 decreases with age, leading to skin aging, but targeting microRNA-203b-3p may help maintain its levels and improve skin health.
40 citations
,
July 2013 in “Skin Pharmacology and Physiology” Male skin gets drier and more alkaline as it ages, which may need different skincare than women's skin.
11 citations
,
February 1982 in “Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis” A new method can detect mutations in mice by observing changes in hair follicle cells.
12 citations
,
May 2003 in “Journal of dermatological science” Hsc70 protein may influence hair growth by responding to androgens.
3 citations
,
February 2025 in “Journal of PHYSIOLOGICAL ANTHROPOLOGY” Certain genes are linked to skin aging, like wrinkles and pigmentation changes.
4 citations
,
July 2025 in “Annals of the New York Academy of Sciences” Combining skeletal and molecular anthropology improves identifying human remains.
January 2008 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” Healthy aging can be promoted through physical activity, lifestyle changes, and certain treatments.