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Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Targeting specific molecular pathways may improve treatments for chemoresistant cancers.

Triboelectric nanogenerators can power wearable medical devices for long-term self-treatment and monitoring.

Perilla frutescens is a versatile herb with health benefits and potential in food and industrial uses.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

ABCD1 gene mutations cause adrenomyeloneuropathy, leading to symptoms like limb weakness and spasticity, with management focusing on rehabilitation and spasticity treatment.

Neuroregulation is crucial for skin wound healing and can be targeted to improve recovery.

Nano-phytopharmaceuticals show promise but need more research for safe, effective use in treating certain disorders.

Kidney-yang deficiency syndrome causes hormonal imbalances and various physical symptoms.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Adding a second method to PROTACs could improve cancer treatment.

Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.

In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.

Autophagy helps keep skin healthy and may improve treatments for skin diseases.

Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.

The effect of GLP-1 RAs on erectile function is unclear and needs more research.

Tumor proteins can both promote and suppress cancer, depending on the situation.

Multitarget drugs are needed to better treat complex diseases.

TSG from Polygonum multiflorum may help with anti-aging by protecting the brain, heart, bones, and hair.

No medications for alcohol dependence have been approved for marketing yet.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Copper-quercetin complexes could be effective in treating cancer, infections, and promoting bone healing.

The secretome from mesenchymal stromal cells shows promise for improving facial nerve injury treatment.

A mild botulinum toxin injection improved sperm production and movement in aging mice.

Ovalbumin–aluminum sensitization causes increased pain sensitivity and nerve changes in mice.

FMH foods may help manage post-acute COVID-19 symptoms safely and easily.

Hydrogels combined with extracellular vesicles and 3D bioprinting improve wound healing.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.