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Adenosine Increases Anagen Hair Growth And Thick Hairs In Japanese Women With Female Pattern Hair Loss: A Pilot, Double-Blind, Randomized, Placebo-Controlled Trial

research Adenosine increases anagen hair growth and thick hairs in Japanese women with female pattern hair loss: A pilot, double-blind, randomized, placebo-controlled trial

33 citations , December 2008 in “Journal of Dermatology”

Adenosine lotion improves hair growth and thickness in women with hair loss.

research Topical eflornithine hydrochloride improves the effectiveness of standard laser hair removal for treating pseudofolliculitis barbae: A randomized, double-blinded, placebo-controlled trial

26 citations , January 2012 in “Journal of the American Academy of Dermatology”

Eflornithine cream makes laser hair removal more effective for treating pseudofolliculitis barbae.

research Platelet-rich Plasma for the Treatment of Erectile Dysfunction: A Prospective, Randomized, Double-blind, Placebo-controlled Clinical Trial

20 citations , April 2023 in “The Journal of Urology”

PRP is safe but not more effective than a placebo for treating mild to moderate erectile dysfunction.

Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study

research Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study

19 citations , May 2017 in “Dermatologic Surgery”

Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.

Curcuma Aeruginosa Roxb. Essential Oil Slows Hair Growth and Lightens Skin in Axillae: A Randomized, Double-Blinded Trial

research Curcuma aeruginosa Roxb. essential oil slows hair-growth and lightens skin in axillae; a randomised, double blinded trial

18 citations , December 2016 in “Phytomedicine”

Curcuma aeruginosa essential oil effectively reduces hair growth and lightens underarm skin.

A Spermidine-Based Nutritional Supplement Prolongs the Anagen Phase of Hair Follicles in Humans: A Randomized, Placebo-Controlled, Double-Blind Study

research A spermidine-based nutritional supplement prolongs the anagen phase of hair follicles in humans: a randomized, placebo-controlled, double-blind study

8 citations , October 2017 in “Dermatology practical & conceptual”

A spermidine-based supplement may help hair grow longer by keeping it in the growth phase.

research The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma (PRP) on Hair Density and Diameter in Androgenetic Alopecia (AGA): A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study.

6 citations , May 2021 in “Aesthetic Surgery Journal”

Higher cell number PRP improves hair density and diameter more than lower cell number PRP.

Platelet-Rich Plasma for Androgenic Alopecia: A Randomized, Placebo-Controlled, Double-Blind Study and Combined Mice Model Experiment

research Platelet‐rich plasma for androgenic alopecia: A randomized, placebo‐controlled, double‐blind study and combined mice model experiment

6 citations , March 2021 in “Journal of Cosmetic Dermatology”

PRP injections promote hair growth and increase hair density in androgenic alopecia.

Efficacy and Safety of 3% Minoxidil Versus Combined 3% Minoxidil / 0.1% Finasteride in Male Pattern Hair Loss: A Randomized, Double-Blind, Comparative Study

research Efficacy and safety of 3% minoxidil versus combined 3% minoxidil / 0.1% finasteride in male pattern hair loss: a randomized, double-blind, comparative study.

6 citations , October 2012 in “PubMed”

The combined treatment of 3% minoxidil and 0.1% finasteride is more effective in improving hair loss than 3% minoxidil alone, with similar side effects.

Safety And Efficacy Assessment Of Red Ginseng Oil (RXGIN) In Men With Lower Urinary Tract Symptoms In A Randomized, Double-Blind, Placebo-Controlled Trial

research Safety and Efficacy Assessment of Red Ginseng Oil (RXGIN) in Men with Lower Urinary Tract Symptoms in a Randomized, Double-Blind, Placebo-Controlled Trial

5 citations , August 2023 in “The World Journal of Men s Health”

Red ginseng oil improves urinary symptoms and some sexual functions in men safely.

Proxalutamide Improves Inflammatory, Immunologic, and Thrombogenic Markers in Mild-to-Moderate COVID-19 Males and Females: An Exploratory Analysis of a Randomized, Double-Blinded, Placebo-Controlled Trial Early Antiandrogen Therapy with Proxalutamide

research Proxalutamide Improves Inflammatory, Immunologic, and Thrombogenic Markers in Mild-to-Moderate COVID-19 Males and Females: an Exploratory Analysis of a Randomized, Double-Blinded, Placebo-Controlled Trial Early Antiandrogen Therapy (EAT) with Proxalutamide (The EAT-Proxa Biochemical AndroCoV-Trial)

5 citations , July 2021 in “medRxiv (Cold Spring Harbor Laboratory)”

Proxalutamide improved blood markers related to inflammation, immune response, and clotting in COVID-19 patients, potentially reducing hospitalizations.

Is Low-Level Laser Therapy Useful as an Adjunctive Treatment for Canine Acral Lick Dermatitis? A Randomized, Double-Blinded, Sham-Controlled Study

research Is low‐level laser therapy useful as an adjunctive treatment for canine acral lick dermatitis? A randomized, double‐blinded, sham‐controlled study

5 citations , January 2021 in “Veterinary dermatology”

Low-level laser therapy did not reduce licking or improve lesions in dogs with ALD but did increase hair growth.

research Effectiveness of Low-dose Ethinylestradiol/Cyproterone Acetate and Ethinylestradiol/Desogestrel with and without Metformin on Hirsutism in Polycystic Ovary Syndrome: A Randomized, Double-blind, Triple-dummy Study.

5 citations , July 2020 in “PubMed”

Both oral contraceptives reduced hirsutism in PCOS patients, but adding metformin showed no extra benefit.

Efficacy and Safety of a New 5% Minoxidil Formulation in Male Androgenetic Alopecia: A Randomized, Placebo-Controlled, Double-Blind, Noninferiority Study

research Efficacy and safety of a new 5% minoxidil formulation in male androgenetic alopecia: A randomized, placebo‐controlled, double‐blind, noninferiority study

5 citations , April 2018 in “Journal of Cosmetic Dermatology”

New 5% minoxidil formula safely and effectively treats male hair loss.

research Comparison of the efficacy and safety of using 0.01% versus 0.03% bimatoprost for the treatment of eyebrow hypotrichosis: A randomized, double‐blind, split‐face, comparative study

4 citations , July 2019 in “Journal of cosmetic dermatology”

Both 0.01% and 0.03% bimatoprost safely improve eyebrow fullness, with a patient preference for the 0.03% concentration.

research Effect of Miracle Fruit (Synsepalum dulcificum) Seed Oil (MFSO®) on the Measurable Improvement of Hair Breakage in Women with Damaged Hair: A Randomized, Double-blind, Placebo-controlled, Eight-month Trial.

4 citations , November 2017 in “PubMed”

Miracle fruit seed oil significantly reduces hair breakage in women with damaged hair.

Efficacy and Safety of a Food Supplement Containing L-Cystine, Serenoa Repens Extract, and Biotin for Hair Loss in Healthy Males and Females: A Prospective, Randomized, Double-Blinded, Controlled Clinical Trial

research Efficacy and Safety of a Food Supplement Containing L-cystine, Serenoa repens Extract and Biotin for Hair Loss in Healthy Males and Females. A Prospective, Randomized, Double-blinded, Controlled Clinical Trial

3 citations , January 2017 in “Journal of cosmetology & trichology”

The food supplement with L-cystine, Serenoa repens extract, and biotin safely reduced hair loss and improved hair growth in men and women.

research Efficacy and safety of deuruxolitinib, an oral selective Janus kinase 1/2 inhibitor, in adults with alopecia areata: Results from the THRIVE-AA2 Phase 3, randomized, double-blind, controlled trial

2 citations , November 2025 in “Journal of the American Academy of Dermatology”

The study evaluated the efficacy and safety of deuruxolitinib, a selective Janus kinase 1/2 inhibitor, in treating adults with severe chronic alopecia areata (AA). In a randomized, double-blind, placebo-controlled trial involving 517 patients, deuruxolitinib was administered at doses of 8 mg and 12 mg twice daily. At Week 24, 33.0% of patients on 8 mg and 38.3% on 12 mg achieved significant hair regrowth (SALT score ≤20), compared to only 0.8% in the placebo group, demonstrating a statistically significant improvement (P < .0001). The treatment was well tolerated with mostly mild or moderate adverse events. However, the study did not assess long-term efficacy and safety, indicating a need for further research. Overall, deuruxolitinib shows promise as a treatment option for adults with AA.

research 41701 Efficacy of the Oral JAK1/JAK2 Inhibitor CTP-543 (Deuruxolitinib) in Adult Patients with Moderate to Severe Alopecia Areata: Results from the Multinational Double-Blind, Placebo-Controlled THRIVE-AA1 Phase 3 Trial

2 citations , September 2023 in “Journal of the American Academy of Dermatology”

CTP-543 effectively promotes hair regrowth in adults with moderate to severe alopecia areata.

Evaluation of the Safety and Efficacy of Platelet-Rich Plasma in the Treatment of Female Patients with Chronic Telogen Effluvium: A Randomized, Controlled, Double-Blind, Pilot Clinical Trial

research Evaluation of the safety and efficacy of platelet-rich plasma in the treatment of female patients with chronic telogen effluvium: A randomised, controlled, double-blind, pilot clinical trial

2 citations , April 2022 in “Indian Journal of Dermatology, Venereology and Leprology”

Platelet-rich plasma is a promising and safe treatment for increasing hair density and thickness in women with chronic telogen effluvium.

Efficacy and Safety of Standardized Cinnamon Bark Extract for the Prevention of Chemotherapy-Induced Weight Loss and Alopecia in Patients with Breast Cancer: A Randomized, Double-Blind, and Placebo-Controlled Study

research EFFICACY AND SAFETY OF STANDARDIZED CINNAMON BARK EXTRACT FOR THE PREVENTION OF CHEMOTHERAPY-INDUCED WEIGHT LOSS AND ALOPECIA IN PATIENTS WITH BREAST CANCER: A RANDOMIZED, DOUBLE-BLIND, AND PLACEBO-CONTROLLED STUDY

2 citations , August 2019 in “Asian journal of pharmaceutical and clinical research”

Cinnamon bark extract may help prevent weight loss and hair loss in breast cancer patients during chemotherapy and is safe to use.

research Cervi Parvum Cornu complex for men with lower urinary tract symptoms: a multicenter, randomized, double-blind, placebo-controlled trial

1 citations , September 2023 in “Prostate International”

Cervi Parvum Cornu complex improved urinary symptoms in men without major side effects.

Safety and Efficacy of Orally Administered Cepharanthine in Non-Hospitalized, Asymptomatic or Mild COVID-19 Patients: A Double-Blind, Randomized, Placebo-Controlled Trial

research Safety and Efficacy of Oral administrated Cepharanthine in Non-hospitalized, asymptomatic or mild COVID-19 patients: A Double-blind, Randomized, Placebo-controlled Trial

1 citations , January 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Cepharanthine is safe but not clearly effective in speeding up COVID-19 recovery.

research Correction to: The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma (PRP) on Hair Density and Diameter in Androgenetic Alopecia (AGA): A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study

1 citations , September 2022 in “Aesthetic Surgery Journal”

Efficacy of Intramuscular Injections of Biotin and Dexpanthenol in the Treatment of Diffuse Hair Loss: A Randomized, Double-Blind Controlled Study Comparing Two Brands

research Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double‐blind controlled study comparing two brands

1 citations , July 2022 in “Dermatologic Therapy”

Both brands of biotin and dexpanthenol injections improved hair loss, with Bayer also increasing the ratio of thick to thin hairs.

Efficacy and Safety of Topical Combination of 3% Minoxidil and 0.25% Finasteride Versus 3% Minoxidil Solution in Female-Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study

research Efficacy and safety of topical combination of 3% minoxidil and 0.25% finasteride versus 3% minoxidil solution in female-pattern hair loss: A randomized, double-blind, controlled study

1 citations , August 2018 in “Journal of The American Academy of Dermatology”

Combination of minoxidil and finasteride is more effective in increasing hair diameter than minoxidil alone for female-pattern hair loss.

The Beneficial Effects of an Oriental Herbal Complex Supplement on Women’s Hair and Scalp Conditions: A 24-Week, Randomized, Double-Blind, Placebo-Controlled Study

research The Beneficial Effects of an Oriental Herbal Complex Supplement on Women’s Hair and Scalp Conditions: A 24-week, Randomized, Double-blind, Placebo-controlled Study

1 citations , August 2017 in “Journal of food and nutrition research”

The herbal supplement increased hair thickness and reduced scalp oiliness in women.

Safety and Biopsy Outcomes of a Topical Treatment (SM04554) for Male Androgenetic Alopecia: Results from a Phase 2, Multicenter, Randomized, Double-Blind, Vehicle-Controlled Trial

research Safety and biopsy outcomes of a topical treatment (SM04554) for male androgenetic alopecia (AGA): Results from a phase 2, multicenter, randomized, double-blind, vehicle-controlled trial

1 citations , June 2017 in “Journal of The American Academy of Dermatology”

Topical treatment SM04554 safely promotes hair growth in male baldness.

Efficacy, Safety, and Dose Response of STS01, a Topical Controlled Release Nanoparticle Formulation (Dithranol/Prosilic), in Adults with Mild to Moderate Patchy Alopecia Areata: A Randomized, Double-Blind, Multicenter, Phase 2 Trial

research Efficacy, safety and dose response of STS01, a topical controlled release nanoparticle formulation (dithranol/Prosilic), in adults with mild to moderate patchy alopecia areata: A randomised, double-blind, multicentre, phase 2 trial

April 2026 in “medRxiv”

STS01 1% effectively promotes hair regrowth with minimal side effects.

Improvements in Scalp Elasticity and Hair Properties Following Supplementation with Low-Molecular-Weight Porcine Placental Peptides (Placenderm®): A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

research Improvements in scalp elasticity and hair properties following supplementation with low-molecular-weight porcine placental peptides (Placenderm®): A randomized, double-blind, placebo-controlled clinical trial

February 2026

Placenderm® improves scalp elasticity and hair quality safely.

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