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August 2014 in “Journal of the American Academy of Dermatology” Diphenylcyclopropenone (DPCP) is effective in treating alopecia areata, with most patients showing significant hair regrowth.
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July 2019 in “Journal of Dermatological Science” Increasing alkaline phosphatase in human skin cells helps to grow more hair.
September 2023 in “International journal of molecular sciences” Pinus densiflora extract may help improve memory and reduce brain inflammation.
84 citations
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February 2015 in “Experimental Dermatology” PPARγ is crucial for skin health but can have both beneficial and harmful effects.
Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.
73 citations
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October 2003 in “Journal of Pharmacology and Experimental Therapeutics” Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.
218 citations
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October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
September 2025 in “Wound Repair and Regeneration” GLP-1 receptor agonists may help manage and prevent diabetic foot ulcers.
11 citations
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September 2014 in “International Journal of Molecular Sciences” Mycophenolate helps reverse hair loss effects caused by IFN-γ by activating a key hair growth pathway.
November 2023 in “Cell Proliferation” A protein from fat-derived stem cells, DKK1, is linked to hair loss and blocking it may help treat alopecia areata.
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August 2023 in “Molecules” SH-340 may improve skin barrier and help treat atopic dermatitis.
June 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Prostaglandin D2, found in higher levels in bald scalps, stops hair growth and could be a target for treating hair loss.
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November 2019 in “Scientific reports” The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.
1 citations
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August 2023 in “Journal of Investigative Dermatology” Farudodstat may help treat alopecia areata by protecting hair follicles.
July 2025 in “Ultrasound in Medicine & Biology” UTMD with diclofenac and Doxil® improves cancer treatment by boosting immune response and reducing tumor-supporting cells.
August 1994 in “Journal of dermatological science” Different substances affect hair and skin cell growth in various ways, with some promoting and others inhibiting cell proliferation.
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December 2016 in “Stem Cell Research & Therapy” P311 helps skin stem cells become myofibroblast-like cells, aiding wound healing.
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February 2024 in “Anais Brasileiros de Dermatologia” 46 citations
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November 2004 in “Lipids” PPARs help regulate skin health and could be used to treat skin disorders.
CRH causes hair loss by reducing autophagy and increasing cell death in hair cells.
17 citations
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April 2007 in “Kidney international” Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.
171 citations
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July 2007 in “Journal of Investigative Dermatology” A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
15 citations
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August 2017 in “International Journal of Molecular Medicine” Panax ginseng extract may help prevent hair loss caused by DKK-1.
January 2005 in “Urologia Journal” 5αR inhibitors help slow early prostate cancer cell growth, suggesting combined treatments are needed.
August 1994 in “Journal of dermatological science” Different substances affect hair and skin cell growth in various ways.
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June 2025 in “Stem Cell Research & Therapy” Exosome therapy may help treat diabetic nerve damage, but more research is needed.
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December 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Dexamethasone may cause hair loss by stopping cell growth.
76 citations
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August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
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May 2023 in “Molecules” Polygoni Cuspidati Rhizoma et Radix contains compounds that inhibit certain enzymes.
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May 2023 in “Cells” Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.