research Recent progress in PLGA-based microneedle-mediated transdermal drug and vaccine delivery
PLGA-based microneedles are promising for safe and effective skin delivery of drugs and vaccines.
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research Exosomes derived from human dermal papilla cells promote hair growth in cultured human hair follicles and augment the hair‐inductive capacity of cultured dermal papilla spheres
Exosomes from human skin cells can stimulate hair growth and could potentially be used for treating hair loss.
research Formulation of Sodium Valproate Nanospanlastics as a Promising Approach for Drug Repurposing in the Treatment of Androgenic Alopecia
Sodium Valproate nanospanlastics could be a safe and effective treatment for Androgenic Alopecia, with fewer side effects than minoxidil.
research Early postnatal allopregnanolone levels alteration and adult behavioral disruption in rats: Implication for drug abuse
Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.
research Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations
Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
research Characterisation of Myotonic Dystrophy type I cell models and drug evaluation by a cell- based quantification platform.
Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.
research Microgel emulsion loaded with recombinant oil body as a new drug delivery carrier to promote wound repair
OBEME effectively enhances wound healing and could be a promising carrier for skin treatments.
research Tooth Regeneration: Insights from Tooth Development and Spatial-Temporal Control of Bioactive Drug Release
Tooth regeneration could become possible by controlling how and when bioactive factors are released.
research Experimental and thermodynamic analyses of supercritical CO2-Solubility of minoxidil as an antihypertensive drug
Minoxidil dissolves better in propylene glycol + water than in supercritical CO2.
research Isolation and validation of antimalarial compounds from Phyllanthus emblica leaves for new antimalarial drug development
Phyllanthus emblica leaves show potential for developing new antimalarial drugs with low toxicity.
research Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases
Blocking certain receptors in the lungs might help treat a specific type of asthma.
research Natural products and their derivatives as candidate treatments for hair greying: from drug discovery to molecular mechanisms
Natural products might help treat hair greying.
research Hair Loss in a Hemodialysis Patient after Repetitive Use of the Antipruritic Drug Nalfurafine: Implications of Impaired Angiogenesis for Hair Loss
Stopping nalfurafine reversed hair loss in a hemodialysis patient.
research Inhibition of SARS-CoV-2 entry through the ACE2/TMPRSS2 pathway: a promising approach for uncovering early COVID-19 drug therapies
Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
research Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine
Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
research Development of Fast Reverse Phase Liquid Chromatographic Method for Simultaneous Analysis of Betamethasone Dipropionate and Calcipotriol in Ointments and Bulk Drug
Researchers developed a quick and reliable method to test for betamethasone dipropionate and calcipotriol in ointments and drugs.
research Real-world study of adverse events associated with gepant use in migraine treatment based on the VigiAccess and U.S. Food and Drug Administration’s adverse event reporting system databases
Rimegepant causes more nausea and skin issues, while ubrogepant causes more muscle issues; personalized treatment is important.
research Platycarya strobilacea S. et Z. Extract Has a High Antioxidant Capacity and Exhibits Hair Growth-promoting Effects in Male C57BL/6 Mice
Platycarya strobilacea extract is a strong antioxidant that can grow hair better than minoxidil.
research Development and Invitro Evaluation of Solid Lipid Nano Particles Loaded Topical Gel Containing Combination of Drugs Used In The Better Therapy of Psoriasis
The new gel for psoriasis is effective, stable, and easy to apply.
research New substrates for stem cell control
New materials help control stem cell growth and specialization for medical applications.
research A Study on the Utilization of Dendropanax morbifera Lev. Leaf Extract for Material of Functional Cosmetics and Hair Growth Products
Dendropanax morbifera leaf extract could be good for hair growth and cosmetic products because of its antioxidant properties and growth factor effects.
research Disorders of the hair and scalp.
The document concludes that while some hair and scalp disorders can be treated, hair loss from destroyed follicles is permanent, and damaged hair can only regrow naturally.
research The Increasing Importance of the Hair Follicle Route in Dermal and Transdermal Drug Delivery
Using hair follicles can improve skin drug delivery.
research Understanding Microemulsions and Nanoemulsions in (Trans)Dermal Delivery
Microemulsions and nanoemulsions can effectively deliver drugs through the skin, but more research is needed to understand their differences and mechanisms.
research Nanostructured Lipid Carrier for Hyperpigmentation Treatment - a Dermal Prospective
Nanostructured lipid carriers are effective for treating hyperpigmentation in women aged 30-40.
research Application of microneedle patches for drug delivery; doorstep to novel therapies
Microneedle patches could replace injections but need more development for better use in medicine.
research Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance
Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.
research Preparation and characterization of Betasitosterol-loaded nanostructured lipid carriers for butter enrichment
Researchers made a special butter with added betasitosterol that could be healthier for the heart and stayed good for three months.
research Binary and ternary inclusion complexes of finasteride in HPβCD and polymers: Preparation and characterization
Finasteride complexes with HPβCD and polymers improve solubility, potentially enhancing hair loss treatment.
research Swellable Microneedles in Drug Delivery and Diagnostics
Swellable microneedles could improve drug delivery and diagnostics but need more research on materials and technology integration.