research Skin Manifestations of Rheumatological Diseases
Different rheumatological diseases can cause specific skin problems.
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600-630 / 1000+ results research Drug Repositioning: New Approaches and Future Prospects for Life-Debilitating Diseases and the COVID-19 Pandemic Outbreak
Drug repositioning offers a cost-effective, lower-risk way to treat diseases and pandemics like COVID-19.
research Ichthyosis
The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.
research Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells
Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.
research Frontal fibrosing alopecia: a case series of 65 patients seen in a single Italian centre
The study concluded that severity of Frontal fibrosing alopecia is not linked to how long someone has it, can start before menopause, and eyebrow loss may be an early sign.
research The Contribution of Endogenous and Exogenous Factors to Female Alopecia
Both genetic and lifestyle factors significantly affect female hair loss.
research The Use of Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryos during Organogenesis and Their Role in Regulating the Gene Expression of Normal and Pathological (Stem) Cells
SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.
research Topical Delivery of Fenugreek Seed Extract Loaded Solid Lipid Nanoparticles Based Hydrogels for Alopecia
Fenugreek seed extract in a nanoparticle gel could be a promising new treatment for hair loss.
research Anticonvulsant-Induced Cutaneous Reactions
Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.
research Understanding Microemulsions and Nanoemulsions in (Trans)Dermal Delivery
Microemulsions and nanoemulsions can effectively deliver drugs through the skin, but more research is needed to understand their differences and mechanisms.
research Significance of the follicular pathway for dermal substance penetration quantified by laser Doppler flowmetry
Hair follicles help substances penetrate the skin faster and more effectively.
research MENSTRUAL DISORDERS IN ADOLESCENTS
The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
research Lucio Phenomenon mimicking with Vasculo necrotic Erithema Nodosum Leprosum: A Case Report
A man with severe leprosy developed painless ulcers and numbness, treated successfully with multiple drugs and vitamins.
research Alopecias
Different types of alopecia in children require specific diagnoses and treatments.
research Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases
Abnormal ECM and immune cell interactions can cause skin diseases.
research Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies
Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
research Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research Vesicular Carriers for Follicular Drug Delivery
Deformable vesicular carriers improve drug delivery for skin conditions and systemic treatments.
research Androgens/Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research Epithelial–mesenchymal transition in cutaneous fibrosis disease: from mechanisms to therapy
EMT plays a key role in skin fibrosis and offers new therapy targets.
research Generalized pustular psoriasis responsive to PUVA and oral cyclosporin therapy
A combination of oral cyclosporin and PUVA treatment worked well for a severe skin condition called generalized pustular psoriasis.
research Prolactin: an emerging force along the cutaneous–endocrine axis
Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
research Nanocrystals for Improved Drug Delivery of Dexamethasone in Skin Investigated by EPR Spectroscopy
The study investigated the use of nanocrystals for improved drug delivery of dexamethasone in skin, using EPR spectroscopy. It found that nanocrystals significantly enhanced drug penetration into both intact and barrier-disrupted porcine skin compared to a base cream, with factors of 3 and 2.1, respectively. Nanocrystals facilitated the delivery of 80% of the drug within 30 minutes, attributed to their high drug loading capacity and increased dissolution rate. The study concluded that nanocrystals were a promising alternative for improving the dermal delivery of sparingly soluble drugs like dexamethasone, particularly in treating inflammatory skin lesions.
research Deep Learning-Based Dermatological Condition Detection: A Systematic Review With Recent Methods, Datasets, Challenges, and Future Directions
Deep learning helps detect skin conditions and is advancing dermatology diagnosis and treatment.
research Alopecia Areata
Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
research Skin melanocytes: biology and development
The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
research Stem Cells behind the Barrier
Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
research Under Development JAK Inhibitors for Dermatologic Diseases
New JAK inhibitor drugs show promise for treating skin diseases but need more research on safety and effectiveness.
research Epidemiology, management and the associated burden of mental health illness, atopic and autoimmune conditions, and common infections in alopecia areata: protocol for an observational study series
People with alopecia areata have higher rates of mental health issues, autoimmune diseases, and infections.
research The therapeutic efficacy of mesenchymal stem cells and their extracellular vesicles in the treatment of diverse skin diseases
Mesenchymal stem cells and their vesicles may effectively treat skin diseases, but more research is needed.