research Hair follicle testing-an alternative to urinalysis for drug abuse screening
Hair follicle testing is more reliable and effective for drug screening than urinalysis.
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research The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Screening of dermatology drugs for aberrant use‐patterns: An application of epidemiologic estimates and measures of inequality in drug use
Dermatology drug use in Denmark mostly follows expected patterns, but further checks are needed for any misuse.
research High-content drug screening for rare diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research A review for cell-based screening methods in drug discovery
Cell-based screening methods are useful and cost-effective for drug discovery but have pros and cons.
research Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity
New inhibitors may reduce gut toxicity from cancer drugs.
research Application of the waiting time distribution in a nationwide screening of real‐world dermatology drug utilization for aberrant use patterns
Most dermatology drugs in Denmark are used correctly, with few unusual patterns.
research The Bioengineering of Microspheric Skin Organoids and Their Application in Drug Screening
Microspheric skin organoids can be used for drug testing, identifying Minoxidil as a Wnt pathway activator.
research Development of a 3D In Vitro Model of Dupuytren’s Disease as a Platform for Drug Screening
A 3D model of Dupuytren’s disease was developed for better drug testing.
research Finasteride-loaded nano-lipidic carriers for follicular drug delivery: preformulation screening and Box-Behnken experimental design for optimization of variables
Optimized carriers effectively deliver Finasteride for hair loss treatment.
research In Situ Self-Assembling Liver Spheroids with Synthetic Nanoscaffolds for Preclinical Drug Screening Applications
PCL nanoscaffold-based liver spheroids are effective for drug screening and studying liver toxicity.
research Bridging the organoid translational gap: integrating standardization and micropatterning for drug screening in clinical and pharmaceutical medicine
Standardizing and engineering organoids can improve their use in medicine and drug testing.
research 1419 Pre-clinical in-vitro assays for high throughput screening of drug candidates for protection and restoration of immune privilege in alopecia areata
The research developed methods to test drugs that could protect and restore hair follicle protection in a hair loss condition.
research Skin Organoids for Disease Modelling, Drug Screening and Regenerative Medicine: Recent Advances and Future Perspectives
Skin organoids are improving research but need better blood supply, nerve function, and immune system integration.
research Postscreening follow-up of the Finnish Prostate Cancer Screening Trial on putative prostate cancer risk factors: vitamin and mineral use, male pattern baldness, pubertal development and non-steroidal anti-inflammatory drug use
Late puberty may slightly lower prostate cancer risk, baldness is not linked to overall risk but less so with aggressive types, ibuprofen use may increase risk, and vitamins show no effect on risk.
research Drug repositioning: current approaches and their implications in the precision medicine era
Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.
research Application of 3D Bioprinting Technology for Tissue Regeneration, Drug Evaluation, and Drug Delivery
3D bioprinting is useful for making tissues, testing drugs, and delivering drugs, but needs better materials, resolution, and scalability.
research From bench to babies – drug development for male subfertility
New methods may speed up drug development for male subfertility.
research Solubility Preformulation Screening of Minoxidil in Different Natural Oils Using Experimental and Computational Approaches
Minoxidil dissolves best in shea butter, stearic acid, and rosemary oil, which may improve hair growth treatments.
research Quantitative Models for the Study of Hair Growth in Vivoa
The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.
research Stem and progenitor cells in sebaceous gland development, homeostasis and pathologies
Stem cells are key for the growth, upkeep, and repair of sebaceous glands and for understanding skin disorders.
research New substrates for stem cell control
New materials help control stem cell growth and specialization for medical applications.
research Development of 3-D Microbioreactor Systems for Cell-Based High Throughput Screening
A new 3-D bioreactor system improves drug screening and reduces animal testing.
research Hair follicle organoids: advances in construction, applications, and translational challenges
Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
research Advancements in hydrogel-based design and applications of hair follicle organoids
Hydrogel-based hair follicle organoids could help treat hair loss and improve drug testing.
research The role of 3Rs in the age of One Health: where we are and where we’re going
Innovative methods are reducing animal testing and improving biomedical research.
research Homology Modeling of 5-alpha-Reductase 2 Using Available Experimental Data
Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.
research Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro
A 3D skin model helps study wound healing better than traditional methods.
research Prevalence and Clinical Spectrum of Dermatologic Conditions in Renal Transplant Recipients: A 10-Year Retrospective Cross-Sectional Study
Renal transplant recipients often have skin issues, especially infections, and need regular skin check-ups.
research Polyherbal chocolate supplementation - a novel adjuvant therapy for polycystic ovary syndrome (PCOS)
Polyherbal chocolate may help manage PCOS symptoms.