research Micro-segmental hair analysis: detailed procedures and applications in forensic toxicology
Micro-segmental hair analysis helps detect drug use patterns and estimate drug consumption days.
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30 / 1000+ results research Different localizations of drugs simultaneously administered in a strand of hair by micro‐segmental analysis
Drugs localize differently in hair strands based on their properties.
research Theoretical investigation on the construction of hair follicle membranes and the transdermal drug delivery mechanisms of JAK inhibitors via distinct pathways
JAK inhibitors can enter the skin through hair follicles using a unique pathway.
research B/N-doped carbon nano-onions as nanocarriers for targeted breast cancer therapy
Boron/nitrogen-doped carbon nano-onions improve targeted breast cancer treatment by enhancing drug delivery and reducing side effects.
research Enhancing Cancer Therapy with Hyperthermia: Synergistic Effects with Natural Compounds and Conventional Treatments
Combining hyperthermia with natural compounds and conventional treatments improves cancer therapy effectiveness and reduces side effects.
research Plant-Derived Exosomes: Nano-Inducers of Cross-Kingdom Regulations
Plant-derived exosomes can help deliver drugs and enable communication between different organisms.
research Interaction of Minoxidil with Pigment in Cells of the Hair Follicle: An Example of Binding without Apparent Biological Effects
Minoxidil binds to hair pigment but doesn't affect hair growth.
research Inducing hair follicle neogenesis by defined extracellular factors
Certain factors can start hair growth in adult skin by making cells communicate and form new hair follicles.
research Glycolytic Dysfunction in Granulosa Cells and Its Contribution to Metabolic Dysfunction in Polycystic Ovary Syndrome
Targeting glycolysis may help treat PCOS by improving insulin sensitivity and ovarian function.
research Nanocarrier Systems for Transdermal Drug Delivery
Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
research Effectiveness and Adverse Drug Reaction Mechanisms Associated with Valproic Acid Use: A Cross-Sectional Prospective Study in Indonesia
Valproic acid is effective but often causes side effects like weight gain and hair loss, so personalized treatment is needed.
research Combined Ultrasound and Microneedle for Enhanced Transdermal Delivery: Synergistic Mechanisms and Therapeutic Advances
Combining ultrasound and microneedles improves drug delivery through the skin.
research Cooling-mediated protection from chemotherapy drug-induced cytotoxicity in human keratinocytes by inhibition of cellular drug uptake
Cooling can protect hair follicles from chemotherapy damage by reducing drug uptake.
research Advances in Cell-Mediated Drug Delivery for Dermatologic Diseases: Mechanisms and Current Applications
Cell-mediated drug delivery systems improve skin disease treatment by using living cells for precise, prolonged, and less toxic therapy.
research Using the zebrafish lateral line to uncover novel mechanisms of action and prevention in drug-induced hair cell death
Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.
research Erbium–Yttrium–Aluminum–Garnet Laser Irradiation Ameliorates Skin Permeation and Follicular Delivery of Antialopecia Drugs
Using a special laser can improve how well hair loss treatments get into the skin and hair follicles.
research Skin Structure, Physiology, and Pathology in Topical and Transdermal Drug Delivery
Improving drug delivery through the skin requires understanding skin and using enhancers.
research Application of microneedle patches for drug delivery; doorstep to novel therapies
Microneedle patches could replace injections but need more development for better use in medicine.
research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders
Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
research Targeting integrin pathways: mechanisms and advances in therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Nanotechnological Interventions and Mechanistic Insights into Wound-Healing Events
Nanotechnology can improve wound healing by enhancing treatments and dressings.
research Focused Review on Metal Nanoparticles in Hair Regeneration and Alopecia: Insights into Mechanisms, Assessment Techniques, Toxicity, Regulatory and Intellectual Property Perspectives
Metal nanoparticles show promise for treating hair loss but need more research to ensure safety.
research Hydrogel-Based Strategies for the Prevention and Treatment of Radiation-Induced Skin Injury: Progress and Mechanistic Insights
Hydrogels show promise in preventing and treating skin damage from radiation therapy.
research Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration
Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
research A Comprehensive Review of Mammalian Pigmentation: Paving the Way for Innovative Hair Colour-Changing Cosmetics
Innovative cosmetics could safely change hair color by targeting biological hair pigmentation processes.
research Squarticles as a nanocarrier for targeting minoxidil to hair follicles and dermal papilla cells
Squarticles, tiny particles made from sebum-derived lipids, can effectively deliver minoxidil, a hair growth drug, directly to hair follicles and skin cells, with less skin penetration and more tolerability.
research Structural mechanism of TRPV3 channel inhibition by the plant‐derived coumarin osthole
Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
research Understanding Microemulsions and Nanoemulsions in (Trans)Dermal Delivery
Microemulsions and nanoemulsions can effectively deliver drugs through the skin, but more research is needed to understand their differences and mechanisms.
research Nanocarriers for optimizing the balance between interfollicular permeation and follicular uptake of topically applied clobetasol to minimize adverse effects
Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.
research Drug-induced changes in hair growth
Some drugs can cause hair loss or growth, but hair usually returns to normal after stopping the drug.