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research Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Research and Treatment of Cancer (EORTC) Network Of Core Institutes (NOCI)
BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.
research TRIAMCINOLONE ACETONIDE INTRAMUSCULARLY: EFFECTIVE LONG‐ACTING STEROID THERAPY IN DERMATOLOGIC DISORDERS
Triamcinolone acetonide injections effectively treat skin disorders like eczema and psoriasis.
research In Vivo Evaluation ofEclipta albaExtract as Anticancer and Multidrug Resistance Reversal Agent
Eclipta alba extract may work as an anticancer agent and help reverse drug resistance.
research Chinese Experts Consensus on the Management of Uncommon Dermatophytosis
Experts created guidelines to better diagnose and treat uncommon fungal skin infections.
research Effect of immunosuppressive ppiase inhibitors, cyclosporin A, FK506, ascomycin and rapamycin on hair growth initiation
Cyclosporin A and FK506 can start new hair growth in mice, but ascomycin and rapamycin cannot.
research Natural infection by Microsporum canis in a capuchin monkey
A capuchin monkey with a skin infection was successfully treated with itraconazole.
research An Antifungal for Antidiuresis?
Fluconazole might be a new treatment for a type of diabetes that affects water balance in the body.
research Selective, chemical epilation in the treatment of tinea capitis as contrasted with the diffuse X-ray epilation
Selective chemical epilation effectively treats tinea capitis without harmful side effects.
research Disease progression of dermatophytic pseudomycetoma in a Persian cat
The cat died from a hard-to-treat fungal infection despite various treatments.
research PKCδ/MAPKs and NF-κB Pathways are Involved in the Regulation of Ingenane-Type Diterpenoids from Euphorbia neriifolia on Macrophage Function
Euph E and Euri A from Euphorbia neriifolia help control inflammation and immune response in cells.
research Revival of generalized favus
A woman with a rare scalp infection was cured after one month of medication.
research Acute and 30-day oral toxicity studies of a novel coccidiostat – ethanamizuril
Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.
research The Identification of multi-target Inhibitors of Wolbachia pipientis and Onchocerca volvulus by molecular simulations
Adapalene, Diosmin, and Azelastine could be repurposed to treat onchocerciasis.
research Erosive pustular dermatosis and associated alopecia successfully treated with topical tacrolimus
Topical tacrolimus can effectively treat erosive pustular dermatosis and related hair loss.
research Mechanistic study of Erianin in alopecia areata
Erianin may effectively treat alopecia areata by targeting the immune system.
research Diagnosis and management of tinea infections.
Tinea infections need proper diagnosis and treatment with topical or oral antifungals based on severity and location.
research Fucoidan-derived carbon dots against Enterococcus faecalis biofilm and infected dentinal tubules for the treatment of persistent endodontic infections
Fucoidan-derived carbon dots can effectively treat root canal infections by killing bacteria and are safer than traditional disinfectants.
research Cortexolone 17a-propionate: Preclinical profile of a new topical, skin selective, steroidal antiandrogen
Clofazimine may be effective for treating ashy dermatosis.
research Molecular Docking Studies and ADME Prediction of Novel Isatin Analogs with Potent Anti-EGFR Activity
Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.
research Dermatophytosis in Cats
The document says to treat cat fungal infections with medicine and clean the environment, noting that cats without symptoms can still spread it to humans.
research A method to improve the efficacy of topical eflornithine hydrochloride cream
Using microneedles before applying eflornithine cream can make it more effective at stopping hair growth.
research Effects of immunosuppressive peptidyl-prolyl cis-trans isomerase (PPIase) inhibitors, cyclosporin A, FK506, ascomycin and rapamycin, on hair growth initiation in mouse: immunosuppression is not required for new hair growth
Cyclosporin A and FK506 can start new hair growth without needing immunosuppression.
research Minoxidil induced central serous Chorioretinopathy treated with oral Eplerenone – a case report
Minoxidil can cause a rare eye condition, but it was successfully treated with oral Eplerenone in one case.
research Cordyceps militaris Grown on Germinated Rhynchosia nulubilis (GRC) Encapsulated in Chitosan Nanoparticle (GCN) Suppresses Particulate Matter (PM)-Induced Lung Inflammation in Mice
GCN reduces lung inflammation and damage from air pollution in mice.
research Tinea capitis in adults.
Tinea capitis in adults is best treated with oral terbinafine, but other medications may be needed for resistant infections, and family and pets should be checked to prevent reinfection.
research New-onset Majocchi’s granuloma in two kidney transplant recipients under tacrolimus treatment
Majocchi's granuloma can occur in kidney transplant patients on tacrolimus and can be treated with antifungal medication.
research Hair growth-stimulating effects of cyclosporin A and FK506, potent immunosuppressants
FK506 may stimulate hair growth when applied to the skin.
research Cefalexin
A woman developed a severe skin reaction from the antibiotic cefalexin.
research Escin Activates Canonical Wnt/β-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3β in Cultured Human Dermal Papilla Cells
Escin may help treat hair loss by boosting a specific cell growth pathway.