30 citations
,
February 2022 in “Stem Cell Reviews and Reports” Stem cell treatments may improve burn wound healing.
30 citations
,
May 2014 in “American Journal of Clinical Dermatology” The conclusion is that better understanding and more research are needed to effectively manage follicular and scarring disorders in skin of color, with an emphasis on patient education and cultural awareness.
25 citations
,
February 2019 in “Genomics” Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.
21 citations
,
July 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can still help heal wounds.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
18 citations
,
April 2013 in “PLOS ONE” Mice with autoimmune hair loss showed signs of heart problems.
15 citations
,
June 2015 in “Human Cell” Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.
9 citations
,
January 2018 in “Stem Cells International” Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.
January 2026 in “Asian Journal of Pharmaceutical and Clinical Research” Umbilical cord and cord blood stem cells are promising for treating chronic diseases due to their versatility and ethical acceptability.
November 2025 in “International Journal of Zoology and Applied Biosciences” New technologies like AI, robotics, and stem cells have made hair transplants more effective and natural-looking.
November 2025 in “Nature Communications” Hair growth may involve a pulling force from the outer root sheath.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Platelet-rich Plasma Gel may help treat en coup de sabre scleroderma, improving symptoms and skin quality with minimal side effects.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
232 citations
,
October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
187 citations
,
April 2019 in “npj Regenerative Medicine” Wharton's jelly secretomes are best for promoting blood vessel growth.
150 citations
,
December 2012 in “EMBO Reports” Stem cell self-renewal is complex and needs more research for full understanding.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
98 citations
,
November 2014 in “PLoS ONE” Hyaluronidase speeds up wound healing and reduces inflammation.
88 citations
,
May 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
87 citations
,
January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
76 citations
,
June 2018 in “EMBO Reports” YAP and TAZ proteins are necessary for the development of two types of skin cancer.
75 citations
,
June 2019 in “International Journal of Molecular Sciences” Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.
71 citations
,
September 2006 in “Cell Transplantation” Fetal skin cells from a cell bank heal wounds faster and with less scarring than adult cells.
69 citations
,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
62 citations
,
October 2017 in “JAMA facial plastic surgery” Condensed nanofat with fat grafts effectively improves atrophic facial scars.
61 citations
,
December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
59 citations
,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
57 citations
,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
56 citations
,
March 2016 in “International Wound Journal” Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.