research Heme Oxygenase and the Skin in Health and Disease
HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
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research Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
research Diverse cellular players orchestrate regeneration after wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research Taming of Covid-19: potential and emerging application of mesenchymal stem cells
Mesenchymal stem cells show promise in treating COVID-19 by reducing inflammation and aiding recovery, but more research is needed.
research Differential impact of environmental factors on systemic and localized autoimmunity
Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
research The role of B cell-activating factor system in autoimmune diseases: mechanisms, disease implications, and therapeutic advances
BAFF-targeted therapies can reduce autoimmune disease activity, but more research is needed for precise treatments.
research PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection
PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.
research Bioinformatics analysis of genes associated with the patchy-type alopecia areata: CD2 may be a new therapeutic target
CD2 might be a new treatment target for patchy alopecia areata.
research Lymphatic vessel: origin, heterogeneity, biological functions, and therapeutic targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.
research Oxidative stress and alopecia areata
Oxidative stress may contribute to hair loss in alopecia areata and antioxidants could potentially help as a treatment.
research Aberrant inflammasome activation as a driving force of human autoimmune skin disease
Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.
research Formation of the cornified envelope
The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
research Regulatory T cells: master orchestrators of immune tolerance and tissue homeostasis
Regulatory T cells help control the immune system and could lead to new treatments for diseases.
research Regulation of the innate immune response in rheumatoid arthritis
More research is needed to understand and manage rheumatoid arthritis better.
research Global trends in tertiary lymphoid structures: a bibliometric analysis from 2014 to 2023
Tertiary lymphoid structures are important in immunotherapy and need more research.
research NF-κB in biology and targeted therapy: new insights and translational implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research TCM “medicine and food homology” in the management of post-COVID disorders
Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.
research Characterization of Primary Cilia and Intraflagellar Transport 20 in the Epidermis
Ift20 is essential for hair follicle function and skin cell movement.
research Construction strategies of skin organoids: A review
A unified framework is needed to improve skin organoid construction for research and clinical use.
research Application and progress of induced pluripotent stem in chronic wound healing: a narrative review
Induced pluripotent stem cells could improve chronic wound healing but face safety and effectiveness challenges.
research EXPLORING THE ROLE OF UMBILICAL CORD AND CORD BLOOD IN REGENERATIVE MEDICINE
Umbilical cord and cord blood stem cells are promising for treating chronic diseases due to their versatility and ethical acceptability.
research Stem cell activity shapes the pleiotropic effects of IFN-γ and TGF-β in autoimmune diseases, infections, and cancer, and drives autoimmune flares and remissions
Stem cell activity influences autoimmune disease outcomes by affecting immune responses and tissue regeneration.
research Immunological control of skin development: from homeostasis to developmental pathologies
Immune cells are crucial for normal skin development and their dysfunction can cause skin disorders.
research Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis
Targeting specific cell interactions may help treat skin fibrosis.
research Das weiße Hautfettgewebe initiiert die IL-33-abhängige Expression von Interleukin 4/13 in myeloischen Zellen während einer Entzündung
White fat tissue in the skin helps control inflammation by affecting certain immune cells.
research Immune niches for hair follicle development and homeostasis
Immune cells are crucial for hair growth and preventing hair loss.
research Modulating embryonic signaling pathways paves the way for regeneration in wound healing
Modifying certain signals in the body can help wounds heal without scars and regrow hair.
research Generating detailed intercellular communication patterns in psoriasis at the single-cell level using social networking, pattern recognition, and manifold learning methods to optimize treatment strategies
New insights into cell communication in psoriasis suggest innovative drug treatments.
research Noval advance of histone modification in inflammatory skin diseases and related treatment methods
Histone modification is key in treating chronic inflammatory skin diseases.
research Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals
Aged individuals heal wounds less effectively due to specific immune cell issues.