research A Concept on The Development of The DRDE Series of Compounds for Skin Diseases Using In-Silico ADME And Drug-Likeness Analysis
DRDE-07 shows promise for treating skin diseases due to its favorable properties.
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research Development of Novel Cosmetic Base Using Sterol Surfactant. II. Solubilizing of Sparingly Soluble Ultraviolet Ray Absorbers†
Sterol surfactants can effectively dissolve UV ray absorbers.
research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.
research Determination of traces of silver in human scalp hair slurries by electrothermal atomic absorption spectrometry
research Purpose-limited pharmaceutical product claims under the revised European Patent Convention: A camouflaged attack on generic substitution?
The revised European Patent Convention may limit generic drug use, affecting healthcare professionals' treatment choices.
research Transferosomes: Unique vesicular carriers for effective transdermal delivery
Transferosomes effectively deliver drugs through the skin, improving treatment for skin disorders.
research Multifunctional Hydrogel with Dual Functions of ROS Scavenging and Responsive Antibiotic Release for Synergistic Oral Mucositis Treatment
The hydrogel effectively treats oral mucositis by reducing oxidative damage and bacterial infection.
research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2
A special receptor in sensory nerve endings helps control how they respond to stretching.
research Alkylation of human hair keratin for tunable hydrogel erosion and drug delivery in tissue engineering applications
Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
research Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease
Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
research Molecular insights into the formation of drug-polymer inclusion complex
The research shows how certain drugs can form stable structures with polymers, which is important for making new pharmaceuticals.
research Liposome-Based Carriers for CRISPR Genome Editing
Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.
research Substantivity and After‐Rinsing Hair Growth Promotion of Cationic Microparticles of Minoxidil
Shampoos with more than 0.6% of cationic minoxidil particles can promote hair growth.
research Fluorescence Microscopy Study of the Sorption of Cationic Polymers on Hair
Polymer JR400 sticks to hair but washes off with detergent.
research Effects of semi-permanent hair dyes and conditioning polymers on the colour enhancing properties of shampoo formulations
Shampoos with polymers and dyes help maintain and enhance hair color vibrancy.
research Antioxidant Constituents of Hops (Humulus lupulus L.) as Functional Raw Materials for Cosmetic Applications
Hops can reduce skin irritation and are effective in cosmetics.
research Preparation, characterization and evaluation of finasteride ethosomes
The ethosomal formulation improved finasteride delivery through the skin.
research N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase
Scientists found new, better-working inhibitors for a hormone-related enzyme.
research Adsorptive cathodic stripping determination of minoxidil in pharmaceutical, cream and shampoo products
Researchers developed a sensitive method to measure minoxidil in various products with high accuracy.
research Finasteride/spironolactone
research Cyproterone acetate for hirsutism
Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.
research Hair perms/straighteners and styling agents
Hair perms or treatments seem safe to use up to 3 to 4 times during pregnancy.
research Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene
The new delivery system improved raloxifene's skin absorption and effectiveness against cancer cells.
research VIBRATIONAL SPECTROSCOPIC INVESTIGATION AND MOLECULAR STRUCTURE OF A 5α-REDUCTASE INHIBITOR: FINASTERIDE
Finasteride's molecular properties and active sites were identified using computational methods.
research Expression and distribution patterns of spermine, spermidine, and putrescine in rat hair follicle
Polyamines are abundant in certain parts of rat hair follicles and may play a key role in hair growth.
research Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes
New compounds with carborane showed anti-androgen effects similar to flutamide.
research Reduced graphene oxide/mesoporous cerium oxide nanoparticles-loaded PVA hydrogel with anti-inflammatory, antioxidant effect and acute wound healing promotion under electrical stimulation
The hydrogel speeds up wound healing with electrical stimulation.
research Fast Motions in 5 Alpha Reductase and Its Impact on Enzyme Kinetics
Efficient enzyme function relies on specific residue interactions and structural coordination.
research Synthetic Approaches for Pharmacologically Active Decorated Six-Membered Diazines
The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.
research 924 Efficient genome editing using CRISPR/Cas9 ribonucleoprotein approach in iPS cells for recessive dystrophic epidermolysis bullosa
Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.