Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
April 2023 in “Chinese Medical Journal” Human hair follicle stem cells help repair tendon injuries.
February 2023 in “Materials today bio” The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.
415 citations
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January 2008 in “Cell” NFATc1 controls hair stem cell activity, affecting hair growth and could be a target for hair loss treatments.
365 citations
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March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
211 citations
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March 2011 in “Journal of Lipid Research” A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.
192 citations
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January 2018 in “Burns & Trauma” Current skin substitutes help heal severe burns but don't fully replicate natural skin features.
182 citations
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May 2003 in “Development” Myc activation reduces skin stem cells by affecting cell adhesion.
172 citations
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March 2019 in “The EMBO Journal” FERONIA and LRX proteins help control cell growth in plants by regulating vacuole expansion.
122 citations
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January 2006 in “Molecular & Cellular Proteomics” Human hair contains many proteins, with some being highly abundant and modified.
98 citations
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December 2015 in “The Journal of Cell Biology” Keratin is crucial for skin barrier formation and affects mitochondrial function.
91 citations
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December 2019 in “The EMBO Journal” NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.
91 citations
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November 2008 in “Journal of biological chemistry/The Journal of biological chemistry” DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.
90 citations
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October 2023 in “Advanced Drug Delivery Reviews” Controlling inflammation can help heal diabetic foot ulcers.
87 citations
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March 2015 in “The EMBO Journal” Adult tissue stem cells can adapt and switch roles to help repair and maintain the body.
87 citations
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July 2009 in “Journal of Cell Science” Deleting the CDSN gene causes severe skin and hair problems, leading to death.
85 citations
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March 2008 in “Journal of Cell Science” The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.
84 citations
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September 2008 in “Developmental biology” Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
75 citations
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August 2018 in “Plant physiology” Hydrogen sulfide disrupts protein function and root hair growth in plants by modifying proteins.
70 citations
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June 2023 in “International Journal of Molecular Sciences” Air pollution harms skin health and can worsen skin diseases.
61 citations
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October 2011 in “Experimental dermatology” Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.
58 citations
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July 2018 in “Journal of Allergy and Clinical Immunology” Alopecia areata severity is linked to increased TH1 and TH2 activity.
54 citations
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March 2024 in “Journal of Medicinal Chemistry” N-oxides are important in medicine for improving drug properties and targeting.
49 citations
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December 2022 in “Pharmacological Reviews” Targeting androgen receptors shows promise for treating triple-negative breast cancer, but more research is needed.
49 citations
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January 2017 in “Oxidative Medicine and Cellular Longevity” Eclipta alba extract may help fight cancer and has antioxidant benefits without being toxic.
44 citations
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January 2023 in “New Phytologist” FER and TOR signaling help root hair growth in low temperature and low nitrate conditions.
41 citations
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March 2016 in “The Journal of Clinical Endocrinology & Metabolism” In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.
39 citations
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April 2019 in “The journal of immunology/The Journal of immunology” Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
36 citations
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March 2014 in “Molecular and Cellular Biology” Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.
35 citations
,
November 2021 in “Environmental Health” Environmental health research must address racism to improve health outcomes for BIPOC communities.