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Immunolocalization of a Histidine-Rich Epidermal Differentiation Protein in the Chicken Supports the Hypothesis of an Evolutionary Developmental Link Between the Embryonic Subperiderm and Feather Barbs and Barbules

research Immunolocalization of a Histidine-Rich Epidermal Differentiation Protein in the Chicken Supports the Hypothesis of an Evolutionary Developmental Link between the Embryonic Subperiderm and Feather Barbs and Barbules

22 citations , December 2016 in “PloS one”

A specific protein in chicken embryos links early skin layers to feather development.

research EDA Missense Variant in a Cat with X-Linked Hypohidrotic Ectodermal Dysplasia

June 2024 in “Genes”

A genetic mutation in the EDA gene causes hypohidrotic ectodermal dysplasia in cats.

EDA and EDAR Expression at Different Stages of Hair Follicle Development in Cashmere Goats and Effects on Expression of Related Genes

research EDA and EDAR expression at different stages of hair follicle development in cashmere goats and effects on expression of related genes

12 citations , December 2020 in “Archives animal breeding/Archiv für Tierzucht”

EDA and EDAR are important for hair follicle development in cashmere goats and affect other related genes.

research Identification and characterization of genes for skin and hair disorders

February 2026 in “bonndoc (University of Bonn)”

New gene variants were found for rare skin and hair disorders, improving understanding and treatment.

research MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2

123 citations , November 2012 in “Stem cells”

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

research Screening and Expression of Keratin EST in Xinji Fine Wool Sheep

1 citations , January 2015 in “China Animal Husbandry & Veterinary Medicine”

Four keratin genes are crucial for hair growth in Xinji fine wool sheep.

research Colourless side of the nude mutation: Foxn1 and hair pigmentation

1 citations , April 2008 in “Pigment Cell & Melanoma Research”

Foxn1 is essential for hair pigmentation by directing pigment transfer to hair cells.

research Skin regional specification and higher-order HoxC regulation

3 citations , March 2025 in “Science Advances”

A specific DNA duplication in Polish chickens affects feather shape by altering gene expression.

research POLYCOMB REPRESSIVE COMPLEX 1 IS REQUIRED TO MAINTAIN STEM CELL IDENTITY AND TO PRESERVE ADULT TISSUE HOMEOSTASIS.

January 2020 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)”

Polycomb Repressive Complex 1 is crucial for keeping stem cells stable and maintaining healthy adult tissues.

research LB999 Role of transcription factor Ovol2 in skin epithelial regeneration and repair

September 2017 in “Journal of Investigative Dermatology”

Ovol2 is essential for normal skin and hair regeneration.

research Autosomal dominant monilethrix with incomplete penetrance due to a novel KRT86 mutation in a Chinese family

April 2024 in “Anais Brasileiros de Dermatologia”

research Live-cell Imaging and Analysis of Germline Stem Cell Mitosis in Caenorhabditis elegans

6 citations , January 2022 in “BIO-PROTOCOL”

The protocol allows easy imaging of dividing cells in C. elegans and can be used for other organisms.

research A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle

26 citations , September 2018 in “Journal of Molecular Cell Biology”

Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.

research 17β-Estradiol Increases APE1/Ref-1 Secretion in Vascular Endothelial Cells and Ovariectomized Mice: Involvement of Calcium-Dependent Exosome Pathway

9 citations , August 2021 in “Biomedicines”

17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.

research Expression of E6 and E7 papillomavirus oncogenes in the outer root sheath of hair follicles extends the growth phase and bypasses resting at telogen.

10 citations , October 2000 in “PubMed”

E6/E7 oncogenes in hair follicles cause continuous hair growth by skipping the resting phase.

research Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos

7 citations , September 2019 in “Journal of Cellular Physiology”

Akt2 protein is essential for normal cell division in early mouse embryos.

research Gene expression patterns during palatal shelf fusion

August 2004 in “Journal of the American College of Surgeons”

Several genes, including Hox-7A, Stra6, and Lim-1, are involved in normal palate formation.

research A WWP2–PTEN–KLF5 signaling axis regulates odontoblast differentiation and dentinogenesis in mice

9 citations , July 2022 in “Journal of Biological Chemistry”

WWP2 is crucial for tooth development in mice.

research Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

990 citations , October 1999 in “Development”

Activated LEF/TCF complexes are crucial for hair development and cycling.

research Cell Cycle Regulation and Regeneration

27 citations , January 2012 in “Current Topics in Microbiology and Immunology”

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

research Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix

175 citations , August 1997 in “Nature Genetics”

research Loss-of-Function Mutations in HOXC13 Cause Pure Hair and Nail Ectodermal Dysplasia

74 citations , October 2012 in “The American Journal of Human Genetics”

Mutations in the HOXC13 gene cause hair and nail development issues.

research Functional mapping of the mouse hairless gene promoter region

January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)”

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

research Distinct tooth regeneration systems deploy a conserved battery of genes

September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Different fish use the same genes to regrow teeth.

research Expression of Potential Dermal Progenitor Cell Markers in the Tumour and Stroma of Skin Adnexal Malignant and Benign Tumours

3 citations , April 2019 in “Stem cells international”

Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.

research The occurrence of the ε-(γ-glutamyl)lysine cross-link in the medulla of hair and quill

49 citations , January 1972 in “Biochimica et Biophysica Acta (BBA) - Protein Structure”

research Molecular mechanisms of ectodermal dysplasia syndromes

3 citations , June 2004 in “Työväentutkimus Vuosikirja”

Ectodermal dysplasia syndromes are caused by disruptions in key signaling pathways affecting tooth and hair development.

research Integrating whole-genome re-sequencing and transcriptome data to reveal the molecular mechanism of TBX5 gene regulating feathered feet in Guangxi native chickens

2 citations , February 2025 in “Poultry Science”

TBX5 gene influences feathered feet in Guangxi chickens by affecting cell growth and movement.

research Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis

208 citations , November 2000 in “Development”

Edar and Eda proteins are crucial for proper tooth development.

research 591 Chromatin architectural protein CTCF regulates terminal keratinocyte differentiation in the developing epidermis and hair follicles

April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

CTCF protein is essential for skin and hair follicle development in mice.

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