research Drug repositioning using in silico compound profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
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research Air pollution and skin diseases: Adverse effects of airborne particulate matter on various skin diseases
Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline
The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
research The 46th Annual Meeting of the Irish Endocrine Society Meeting Programme and Abstracts 2022
Electrical stimulation with a low-calorie diet reduces appetite, weight, and blood pressure in obese people with sleep apnea.
research Early postnatal allopregnanolone levels alteration and adult behavioral disruption in rats: Implication for drug abuse
Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.
research The hydroxypropyl‐β‐cyclodextrin‐minoxidil inclusion complex improves the cardiovascular and proliferative adverse effects of minoxidil in male rats: Implications in the treatment of alopecia
A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.
research Selected abstracts from the 47th meeting of the Irish Endocrine Society Sligo, 24th & 25th November 2023
Continuous glucose monitoring and GLP-1 receptor agonists improve diabetes management, but personalized care and education are crucial.
research Post-marketing safety profile of cladribine in multiple sclerosis: a disproportionality analysis based on the FDA adverse event reporting system
Cladribine has known risks and potential new safety concerns, requiring careful monitoring.
research Natural products and their derivatives as candidate treatments for hair greying: from drug discovery to molecular mechanisms
Natural products might help treat hair greying.
research Bibliometric Study of Adaptogens in Dermatology: Pharmacophylogeny, Phytochemistry, and Pharmacological Mechanisms
Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.
research Five-Alpha Reductase Inhibitor and Breast Cancer Risk in Men: A Systematic Review
Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.
research Minoxidil
Minoxidil is effective for hair growth and safe for long-term use.
research Safety Considerations and Monitoring in Patients Treated with Systemic Medications for Acne
Some acne medications have side effects; doctors should educate patients and may not need to do frequent lab tests for all.
research Safety concerns regarding 5α reductase inhibitors for the treatment of androgenetic alopecia
5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
research Amitriptyline-induced Telogen Effluvium in a Patient with Cervical Disc Prolapse: A Case Report
Amitriptyline can cause temporary hair loss, which stops after discontinuing the drug.
research Development of fluridil, a topical suppressor of the androgen receptor in androgenetic alopecia
Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
research Index
Chemotherapy can cause skin issues and hair loss, and this guide explains how to manage them.
research Androgenetic alopecia: effects of oral finasteride on hormone profile, reproduction and sexual function
Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.
research Evaluación de la seguridad de minoxidil oral a dosis bajas en el tratamiento de la alopecia
Low-dose oral minoxidil is generally safe for treating hair loss, with mostly mild side effects.
research Telogen Effluvium and Metabolic Stress in Modern Weight Loss Interventions: A Narrative Clinical Review
Hair loss from weight-loss treatments is usually temporary and reversible.
research Diet in dermatology: Revisited
Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.
research Therapeutic Potential of Vitex negundo for the Treatment of Polycystic Ovarian Disease (PCOD): A Review
Vitex negundo may help treat PCOD, but more human studies are needed.
research Increased Incidence and Risk of Hair Loss with Glucagon-like Peptide 1 Receptor Agonists: A Real-World Multicentre Cohort Study
GLP-1RA therapy may increase the risk of hair loss.
research Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for the Screening of Steroid 5-α Reductase in Human and Fish Cell Lines
A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
research Persistent Sexual Dysfunction and Suicidal Ideation in Young Men Treated with Low-Dose Finasteride: A Pharmacovigilance Study
Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.
research The Effect of Finasteride on Serum Cortisol and testosterone Levels in Rats
Finasteride lowers cortisol and raises testosterone levels in rats.
research Review of the effects of 17α-estradiol in humans: a less feminizing estrogen with neuroprotective potential
17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
research Oral medications for central serous chorioretinopathy: a literature review
Some oral medications may help treat central serous chorioretinopathy, especially eplerenone, but more research is needed.
research Understanding Polycystic Ovary Syndrome
PCOS affects women's hormones and metabolism, but can be managed with lifestyle changes and treatments.