989 citations
,
August 2007 in “The Lancet” PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.
January 2025 in “International Journal for Research Trends and Innovation” PCOS management benefits from combining traditional herbs, modern medicine, and lifestyle changes.
7 citations
,
January 2024 in “Medicinska istrazivanja” PCOS causes hormonal imbalances, irregular periods, and can lead to infertility, obesity, and mental health issues.
6 citations
,
September 2023 in “International journal of molecular sciences” Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.
1 citations
,
August 2023 in “Curēus” Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.
January 2025 in “Biomedicines” High testosterone levels can harm fertility by disrupting the LIF signaling pathway in the uterus.
January 2025 in “International Journal of Pharmaceutical Research and Applications” PCOS causes hormonal imbalance, leading to symptoms like irregular periods and infertility.
March 2024 in “Antioxidants” Excessive blue light harms eye cells and disrupts sleep patterns.
21 citations
,
December 2015 in “Development Growth & Differentiation” DHT is crucial for urethral formation, and its disruption can affect masculinization and lead to hypospadias.
March 2026 in “Cleveland Clinic Journal of Medicine” PCOS diagnosis and management have improved with new guidelines for personalized care.
2 citations
,
January 2017 PCOS is a common hormonal disorder in women that can lead to various health issues and requires comprehensive management.
July 2023 in “Biomolecules” The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.
January 2011 in “Medicina interna de México” The document concludes that treating the underlying causes of telogen effluvium usually results in hair regrowth.
6 citations
,
October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
Individualized treatment improves symptoms and quality of life for women with PCOS.
44 citations
,
May 2012 in “Endocrinology” High levels of androgens during early development may cause PCOS-like symptoms.
3 citations
,
June 2025 in “Drug Design Development and Therapy” Targeting glycolysis may help treat PCOS by improving insulin sensitivity and ovarian function.
2 citations
,
January 2015 in “Springer eBooks” Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.
260 citations
,
July 2010 in “Cell” Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
258 citations
,
July 2016 in “Reproductive Biology and Endocrinology” The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
176 citations
,
June 2017 in “Sexual Medicine Reviews” Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.
37 citations
,
April 2011 in “Journal of Biological Chemistry” LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
31 citations
,
September 2006 in “International journal of gynaecology and obstetrics” New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.
29 citations
,
February 2018 in “Genetics research international” Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
29 citations
,
January 2014 in “Frontiers in physiology” Understanding and tracking our body's natural daily rhythms could help improve heart health.
25 citations
,
July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
5 citations
,
March 2015 in “Women's Health” The document concludes that diagnosing PCOS requires a thorough approach, considering various symptoms and risks, and calls for improved methods to identify PCOS types and prevent diabetes.
December 2021 in “THE THERAPIST (Journal of Therapies & Rehabilitation Sciences)” PCOS is common, affects fertility, and needs early diagnosis and lifestyle changes for management.
19 citations
,
March 2017 in “Scientific Reports” HAT-L4 is crucial for preventing body fluid loss by maintaining skin barrier integrity.
19 citations
,
May 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” The type 3 IP3 receptor is important for controlling hair loss and growth.