research An Analytical Framework for the Selective Extraction and Determination of Nine Multiclass Endocrine-Disrupting Chemicals from Haircare Products
Haircare products may expose users to harmful chemicals despite regulations.
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research Testosterone therapy for transgender men
Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.
research Comparison of cyproterone acetate plus ethinyl estradiol and finasteride in the treatment of hirsutism
Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
research Finasteride inhibits the progesterone-induced spike-wave discharges in a genetic model of absence epilepsy
Finasteride blocks progesterone's effect on absence seizures in rats.
research Endocrine profile of the VCD-induced perimenopausal model rat
The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.
research The effects of statins on hyperandrogenism in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials
Statins can reduce androgen levels and improve symptoms in women with PCOS.
research Pharmaceutical and Pharmacological Evaluation of the Effect of Nano-Formulated Spironolactone and Progesterone on Inflammation and Hormonal Levels for Managing Hirsutism Experimentally Induced in Rats
research Therapeutic Effect of Superficial Scalp Hypothermia on Chemotherapy-Induced Alopecia in Breast Cancer Survivors
Scalp cooling effectively reduces hair loss in breast cancer patients undergoing chemotherapy.
research Short-Term Side Effects of Low Dose Valproate Monotherapy in Epileptic Children: A Prospective Study.
Low dose valproate in epileptic children mainly causes weight gain and other non-life-threatening side effects.
research Hair Regeneration Effects of Lespedeza bicolor Extract In Vivo and In Vitro
Lespedeza bicolor extract promotes hair growth and increases hair follicle cell growth, potentially making it a better treatment than minoxidil.
research Exploring Hirsutism: Epidemiology, Associated Endocrinal Abnormalities, and Societal Challenges in GCC—A Narrative Review
Hirsutism in GCC countries is influenced by genetics, obesity, and lifestyle, with cultural stigma delaying treatment, highlighting the need for tailored health strategies.
research Cutaneous manifestations of endocrine diseases in children
Endocrine diseases in children often cause skin changes like dryness, redness, acne, hair loss, and more.
research The Immun System Response İn Covıd-19 Infectıon İn Polycystıc Ovary Syndrome
Women with PCOS may have a higher risk of severe COVID-19 due to hormonal imbalances and vitamin D deficiency.
research Dermatological drugs, topical agents, and cosmetics
The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.
research Impact of Reporter Type on Signal Detection of Cancer Therapy-Induced Alopecia: A Hypothesis-Generating Study Using the FDA Adverse Event Reporting System
Reporter characteristics affect detection of hair loss from cancer therapy.
research Cutaneous Side Effects of Modern Targeted Therapy and Immunotherapy in Patients with Dermatological Malignancies
Modern skin cancer treatments can cause skin side effects and hair loss, affecting patients' quality of life.
research Effect of Neurosteroids on Basal and Stress-Induced Oxytocin Secretion in Luteal-Phase and Pregnant Sheep
Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.
research Androgens’ Effects across the Lifespan in Men and Animal Models
Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research Spironolactone
Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.
research Effects of Lespedeza Cuneata aqueous extract on testosterone-induced prostatic hyperplasia
Lespedeza cuneata extract may help treat enlarged prostate.
research GLP-1 Receptor Analogs: Evidence Linking to Effect on Metabolic and Reproductive Functions in Patients with PCOS and Obesity
GLP-1 receptor analogs may help improve metabolism and reproductive health in people with PCOS and obesity.
research Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies
Caffeine can boost health, prevent diseases, and improve performance, with new methods enhancing its benefits.
research Advances in polymeric nano-delivery systems targeting hair follicles for the treatment of acne
Polymer-based nanocarriers can improve acne treatment by delivering drugs through hair follicles more effectively.
research Novel modulatory effects of neurosteroids and benzodiazepines on excitatory and inhibitory neurons excitability: a multi-electrode array recording study
Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.
research Saturable Binding of Finasteride to Steroid 5α-reductase as Determinant of Nonlinear Pharmacokinetics
Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.
research New effects of caffeine on corticotropin‐releasing hormone (CRH)‐induced stress along the intrafollicular classical hypothalamic–pituitary–adrenal (HPA) axis (CRH‐R1/2, IP3‐R, ACTH, MC‐R2) and the neurogenic non‐HPA axis (substance P, p75NTRand TrkA) inex vivohuman male androgenetic scalp hair follicles
Caffeine may help reduce stress-induced hair loss.
research Restricted effects of androgens on glucocorticoid signaling in the mouse prefrontal cortex and midbrain
Androgens can affect glucocorticoid signaling in specific mouse brain areas.
research The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial
Magnesium supplements improved quality of life for women with polycystic ovary syndrome, but didn't help with acne, hair loss, or abnormal bleeding.
research The Biomolecular Effects of Finasteride on Male Rat Brain during Administration and after Discontinuation
Finasteride temporarily suppresses brain activity, but some effects last even after stopping.