35 citations
,
May 2015 in “Arquivos De Gastroenterologia” Women with PCOS are more likely to have fatty liver disease and worse metabolic health.
December 2025 in “Annals of the College of Medicine Mosul/Annals of the College of Medecine” Metformin reduces insulin resistance in PCOS, but combining it with finasteride offers extra benefits.
5 citations
,
September 2011 in “Andrologia” Finasteride use may be linked to rare testicular tumor, but more research needed.
55 citations
,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
August 2019 in “Journal of the American Academy of Dermatology” Frontal fibrosing alopecia may be caused by an autoimmune reaction and hormonal imbalance.
7 citations
,
November 2003 in “Current Opinion in Obstetrics & Gynecology” Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.
9 citations
,
May 2021 in “Immunological Reviews” Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
May 2019 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Frontal fibrosing alopecia mostly affects postmenopausal women, with diagnosis often delayed by 3 years.
April 2025 in “Indian Journal of Dermatology” A rare, benign facial tumor called fibrofolliculoma was successfully treated with surgery.
2 citations
,
May 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Fibronectin is crucial for hair stem cell function and regeneration.
May 2026 in “Cell Reports Medicine” FR-1 reduces skin scarring and promotes healing without harmful effects.
A woman's excess male hormone symptoms were caused by a rare benign tumor in her ovary.
5 citations
,
July 2020 in “PubMed” Both oral contraceptives reduced hirsutism in PCOS patients, but adding metformin showed no extra benefit.
1 citations
,
October 2024 in “Cureus” Women with PCOS have higher irisin levels, which may affect their metabolism and hormones.
January 2026 in “Clinical Cosmetic and Investigational Dermatology” Early diagnosis and targeted anti-inflammatory treatments can improve outcomes in androgenetic alopecia with perifollicular inflammation and fibrosis.
December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)” Estrogen speeds up hair follicle cell death, causing early hair growth cycle changes, but only if a specific receptor is present.
June 2025 in “International Journal of Molecular Sciences” Targeting EMT and fibrotic remodeling may help treat androgenetic alopecia.
April 2024 in “Journal of Cytology” A rare skin tumor with bone formation was successfully removed without recurrence.
40 citations
,
January 2013 in “International journal of trichology” Perifollicular erythema can indicate active frontal fibrosing alopecia.
October 2025 in “International Wound Journal” Gamma-irradiated amniotic fluid improves healing and reduces thickness of hypertrophic scars.
27 citations
,
April 2011 in “Folia Histochemica et Cytobiologica” DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.
14 citations
,
January 2020 in “Frontiers in Endocrinology” OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.
October 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” L-PRP and P-PRP reduced endometriosis in rats, but not significantly more than saline.
28 citations
,
October 1984 in “Journal of Investigative Dermatology”
1 citations
,
December 1998 in “PubMed” Surgery on a 68-year-old woman with an ovarian tumor led to reduced hirsutism and normal testosterone levels.
June 2022 in “Biomedical reports” STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.
15 citations
,
April 1997 in “Muscle & Nerve” 5 citations
,
April 1997 in “Muscle & Nerve”
October 2024 in “Journal of the Endocrine Society” Rare ovarian tumors can cause hyperandrogenism, even if imaging appears normal.
4 citations
,
January 2014 in “Dermatology” A woman with acne and baldness was found to have a rare ovarian condition but successfully had a child through fertility treatment.