research Stem-cell therapy in dermatology – Challenges and opportunities
Stem-cell therapy shows promise for skin conditions but needs more research.
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research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity
The human scalp hair bulb contains different types of melanocytes with varying abilities to produce melanin.
research Fatty acids and related lipid mediators in the regulation of cutaneous inflammation
Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
research Co-expression of PADI isoforms during progenitor differentiation enables functional diversity
Different PADI isoforms help cells develop diverse functions.
research Attenuation of Dickkopf 1-Induced Hair Growth Inhibition in Cultured Human Hair Follicles by Tianeptine
Tianeptine may help prevent hair loss by promoting hair growth and reducing cell death.
research Dermal niche signaling and epidermal stem cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Developmental Mechanisms Controlling Cell Fate, Evolution of
The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.
research Engineering immune-competent hair follicle microphysiological systems: from organoid assembly to dynamic immune modelling
Hair follicle systems are being engineered to better mimic natural hair follicles for studying hair disorders and testing treatments.
research Spatiotemporal dynamics of mammalian wound healing
Understanding wound healing involves coordinating different phases and areas to improve treatment strategies.
research Diversity of Adult Stem Cell Niches in the Dermal Compartment of Skin
The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
research Research advances of tissue-derived extracellular vesicles in cancers
Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.
research A Window into Mammalian Basement Membrane Development: Insights from themTurq2-Col4a1Mouse Model
The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.
research Fibroblast heterogeneity: implications for human disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Exogenous IGF-1 promotes hair growth by stimulating cell proliferation and down regulating TGF-β1 in C57BL/6 mice in vivo
IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.
research Advancements in research on the immune-inflammatory mechanisms mediated by NLRP3 inflammasome in ischemic stroke and the regulatory role of natural plant products
Natural plant products like Proanthocyanidins and curcumin may help treat ischemic stroke by reducing inflammation.
research Runx Family Genes in Tissue Stem Cell Dynamics
Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
research Cell-free adipose extract inhibits hypertrophic scar formation through collagen remodeling and antiangiogenesis
High-concentration cell-free adipose extract reduces scar formation and improves scar appearance.
research The role of Extracellular Vesicles in Alopecia and its Treatment
Extracellular vesicles could help treat hair loss by influencing hair growth cycles.
research The non-neuronal and nonmuscular effects of botulinum toxin: an opportunity for a deadly molecule to treat disease in the skin and beyond
Botulinum toxin has potential for treating various skin conditions and improving wound healing.
research Hair Growth‐Promoting Effect of Carthamus tinctorius Floret Extract
Safflower (Carthamus tinctorius) extract helps hair grow and could be used in hair products.
research Dopa oxidase activity in the hair, skin and ocular melanocytes is increased in the presence of stressed fibroblasts
Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
research Therapeutic potential and pharmacological insights of total glucosides of paeony in dermatologic diseases: a comprehensive review
Total glucosides of paeony can help treat skin conditions but need more research for clinical use.
research Hair Growth Promoting Effect of Hottuynia cordata Extract in Cultured Human Hair Follicle Dermal Papilla Cells
Houttuynia cordata extract may help hair grow by improving cell survival and increasing cell growth.
research TGFβ and cancer metastasis: an inflammation link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer
Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
research Interfacial Adipose Tissue in Systemic Sclerosis
Unique fat cells near fibrotic areas contribute to systemic sclerosis progression.
research Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
research Androgen receptor: A promising therapeutic target in breast cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
research Regulation of Semaphorin3A in the process of cutaneous wound healing
Sema3A can both slow and speed up wound healing, depending on its form and combination with EGF.
research Discovering New Progenitor Cell Populations through Lineage Tracing and In Vivo Imaging
New methods have helped find cells that create other cells in the body.