April 2019 in “Journal of Investigative Dermatology” Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
13 citations
,
April 1964 in “PubMed” Phosphatide distribution in mouse skin remains consistent in both normal and cancerous growths.
93 citations
,
April 2012 in “International Journal of Cosmetic Science” Improving skin barrier and using antifungal treatments can help manage dandruff.
81 citations
,
June 2012 in “European journal of human genetics” Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.
40 citations
,
June 2011 in “Journal of biological chemistry/The Journal of biological chemistry” FA2H is essential for normal fur and sebum production in mice.
1 citations
,
June 2023 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Vitamin D helps skin stem cells heal wounds by working with a key skin protein.
218 citations
,
May 2014 in “Experimental Dermatology” Skin fat cells help with skin balance, hair growth, and healing wounds.
211 citations
,
May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
132 citations
,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
130 citations
,
August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
107 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
95 citations
,
July 2015 in “European journal of pharmaceutics and biopharmaceutics” Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
82 citations
,
January 2006 in “International review of cytology” Vertebrate skin evolved to be more specialized and complex, especially in land animals.
77 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
25 citations
,
February 2024 in “Biomaterials” Stem cell-derived organoids can improve skin healing.
25 citations
,
July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
18 citations
,
January 2016 in “Elsevier eBooks” Nanotechnology improves cosmetics' effectiveness and safety.
17 citations
,
August 2014 in “The Anatomical Record” Scaffoldin helps form hard skin structures in chicken embryos.
16 citations
,
June 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.
11 citations
,
July 2022 in “International Journal of Molecular Sciences” Tight junctions help control skin shedding and may be targets for treating certain skin conditions.
9 citations
,
August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
8 citations
,
May 2024 in “Advanced NanoBiomed Research” Nanocarriers can improve skin drug delivery but face challenges in clinical use.
7 citations
,
October 2024 in “Cells” Autophagy is essential for proper skin cell development and function.
7 citations
,
October 2024 in “AAPS PharmSciTech” CA-SLN-Ngel significantly reduces cellulite more effectively than regular caffeine gel.
7 citations
,
June 2012 in “Journal of dairy science” Bovine milk fats applied to mouse skin can promote hair growth similar to known hair growth treatments.
6 citations
,
December 2022 in “Cell reports” Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.
6 citations
,
May 2009 in “Cell transplantation” Green tea component EGCG helps keep rat skin grafts viable longer.
2 citations
,
July 2023 in “Cosmetics” Surfactants in shampoos and conditioners remove some but not all lipids from hair, and more research is needed to understand their full impact.
2 citations
,
March 2020 in “International Journal of Molecular Sciences” Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.