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Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny During Cutaneous Wound Repair

research Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny during Cutaneous Wound Repair

46 citations , May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

research Dendritic epidermal T cells secreting exosomes promote the proliferation of epidermal stem cells to enhance wound re-epithelialization

24 citations , March 2022 in “Stem Cell Research & Therapy”

Dendritic epidermal T cells help wounds heal faster by boosting skin stem cell growth.

Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation

research Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation

207 citations , March 2012 in “Development”

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

research Epidermal growth factor and fibroblast growth factor accelerate proliferation of human hair bulb papilla cells and root sheath tibroblasts cultured in vitro

9 citations , March 1987 in “British Journal of Dermatology”

EGF and FGF can boost hair growth by speeding up cell growth.

research Epidermal-Derived Hedgehog Signaling Drives Mesenchymal Proliferation during Digit Tip Regeneration

3 citations , September 2021 in “Journal of Clinical Medicine”

Epidermal signaling helps regenerate fingertip tissue.

research Author response: Type XVII collagen coordinates proliferation in the interfollicular epidermis

June 2017

Type XVII collagen helps control skin cell growth and may have anti-aging effects.

research Decision letter: Type XVII collagen coordinates proliferation in the interfollicular epidermis

April 2017

Type XVII collagen may help prevent skin aging.

research The Wave complex controls epidermal morphogenesis and proliferation by suppressing Wnt–Sox9 signaling

22 citations , March 2019 in “The Journal of Cell Biology”

The Wave complex controls skin growth by suppressing certain signals.

Receptor Activator of NF-κB Stimulates the Proliferation of Epithelial Cells of the Epidermo-Pilosebaceous Unit

research Receptor activator of NF-κB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit

60 citations , March 2011 in “Proceedings of the National Academy of Sciences of the United States of America”

RANK-RANKL signaling is essential for hair growth and skin health.

The Early Region of Trichodysplasia Spinulosa Polyomavirus Drives Proliferation, Altered Differentiation, and Ectopic Expression of Hair Follicle Differentiation Markers in Interfollicular Tail Epidermis

research LB1019 The early region of trichodysplasia spinulosa polyomavirus drives proliferation, altered differentiation, and ectopic expression of hair follicle differentiation markers in interfollicular tail epidermis

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

The early genes of a specific virus can cause abnormal skin cell growth and hair follicle changes.

research The effects of low intensive pulse magnetic field on the proliferation and differentiation of epidermal stem cells during wound healing process

January 2006 in “Zhongguo linchuang jiepouxue zazhi”

Low intensive pulse magnetic fields can speed up wound healing by boosting skin stem cell growth and development.

research 1α,25-Dihydroxyvitamin D3 accelerates skin wound re-epithelialization by promoting epidermal stem cell proliferation and differentiation through PI3K activation: an in vitro and in vivo study

2 citations , January 2025 in “Brazilian Journal of Medical and Biological Research”

Vitamin D3 speeds up skin healing by helping skin stem cells grow and develop.

research Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease

85 citations , March 2008 in “Journal of Cell Science”

The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.

research GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis

24 citations , December 2013 in “Archives of Dermatological Research”

research Photobiomodulation Facilitates Rat Cutaneous Wound Healing by Promoting Epidermal Stem Cells and Hair Follicle Stem Cells Proliferation

12 citations , October 2023 in “Tissue Engineering and Regenerative Medicine”

research The Insulin-like Growth Factor 1 Receptor Is Expressed by Epithelial Cells with Proliferative Potential in Human Epidermis and Skin Appendages: Correlation of Increased Expression with Epidermal Hyperplasia

128 citations , March 1996 in “Journal of Investigative Dermatology”

research Skin-specific expression of a truncated E1a oncoprotein binding to p105-Rb leads to abnormal hair follicle maturation without increased epidermal proliferation.

30 citations , June 1993 in “The Journal of Cell Biology”

The oncoprotein causes abnormal hair growth without increasing skin cancer risk.

research Cutaneous Side Effects in Non-Small Cell Lung Cancer Patients Treated with Iressa (ZD1839), an Inhibitor of Epidermal Growth Factor

116 citations , December 2003 in “Acta Dermato Venereologica”

Iressa often causes skin issues like acne and dryness in lung cancer patients.

research Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development.

107 citations , June 1997 in “PubMed”

EGFR is essential for normal hair development and follicle differentiation.

research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate

57 citations , March 2018 in “International Journal of Molecular Sciences”

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

research The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles

51 citations , January 2004 in “European Journal of Cell Biology”

Human cathepsin V can replace mouse cathepsin L to maintain normal skin and hair in mice.

research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation and Pigmentation Revealed by Molecular Profiling

9 citations , May 2012 in “PLOS ONE”

ILK is essential for skin development, pigmentation, and healing.

research Claudin Expression Modulations Reflect an Injury Response in the Murine Epidermis

9 citations , July 2007 in “Journal of Investigative Dermatology”

Claudin expression changes help the skin respond to injury.

research Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.Akt^WT mice

8 citations , September 2013 in “Molecular carcinogenesis”

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

Alpha-Parvin Is Required for Epidermal Morphogenesis, Hair Follicle Development, and Basal Keratinocyte Polarity

research α-parvin is required for epidermal morphogenesis, hair follicle development and basal keratinocyte polarity

7 citations , March 2020 in “PloS one”

α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.

research Estrogen modulates mesenchymal-epidermal interactions in the adult nipple

4 citations , March 2017 in “Development”

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

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