27 citations
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April 2008 in “Journal of Biological Chemistry” HMG-CoA reductase is crucial for skin wound healing by regulating keratinocyte growth and blood vessel formation.
3 citations
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January 2022 in “Journal of neuroendocrinology” Sex hormones affect brain cells differently in males and females.
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August 2010 in “Letters in Drug Design & Discovery”
123 citations
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December 2015 in “Journal of Neuroendocrinology” New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
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February 2019 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
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January 1985 in “Acta Obstetricia Et Gynecologica Scandinavica” A rare ovarian tumor caused early puberty signs in a 1-year-old girl, but surgery reduced hormone levels.
July 2024 in “Fitoterapia” Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.
October 2024 in “Journal of the Endocrine Society” Estrogen alone may effectively suppress testosterone in some transfeminine individuals.
6 citations
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September 2024 in “Plant Cell & Environment” Chitosan affects root hair growth and callose deposition based on its concentration.
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October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
62 citations
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August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.
22 citations
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January 1995 in “The American Journal of Medicine” Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.
January 2026 in “Molecular Nutrition & Food Research” Gynostemma pentaphyllum and Damulin B help prevent skin aging from UVB by reducing oxidative stress and improving skin health.
11 citations
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May 2022 in “World Journal of Biological Chemistry” Progesterone may help trans women with breast development and health, but more research is needed.
April 2016 in “International Journal of Drug Delivery” The ethosomal formulation improved finasteride delivery through the skin.
January 2004 in “Banca y finanzas: Revista profesional de gestión financiera” Androgens increase pigmentation in certain hamster skin areas, but estrogens can reverse this effect.
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November 2007 in “Neuro-chirurgie/Neurochirurgie” Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.
29 citations
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June 2000 in “Endocrinology” Alopecia in VDR knockout mice is due to impaired hair cycle initiation, not keratinocyte issues.
20 citations
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October 1995 in “PubMed” Knocking out the FGF5 gene in sheep increased wool production and hair-follicle density.
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September 1970 in “Journal of the American Geriatrics Society” Anabolic steroids may help prevent aging effects by reducing toxicity, not by their usual functions.
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April 2002 in “Brain Research” Lower allopregnanolone levels increase stress-related dopamine release in the brain.
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October 2016 in “Oncotarget” Finasteride has a higher risk of reproductive side effects than minoxidil.
July 2026 in “Journal of the American Academy of Dermatology” Estetrol (E4) can help hair grow longer by extending its growth phase.
11 citations
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January 2006 in “Drug development and industrial pharmacy” Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.
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June 2020 in “The Journal of Clinical Endocrinology and Metabolism” Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.
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February 2014 in “Animal Biotechnology” The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.
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December 1998 in “PubMed” Surgery on a 68-year-old woman with an ovarian tumor led to reduced hirsutism and normal testosterone levels.
20 citations
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November 2020 in “Stem Cell Research & Therapy” Enhanced stem cells from the placenta can help treat Graves' eye disease by stopping fat cell growth.