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Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Transamidases are present in the epidermis but their exact role is unclear.

ERG increases SOX9, promoting prostate cancer growth and invasion.

TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.

Overexpressing ATF3 in mice's epithelial cells may lead to oral cancer.

DHT enhances androgen receptor activity more than testosterone, and MAGE-11 influences this activity through specific interactions.

MPA increases cancer spread by boosting Eph A2 activity.

Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.

Controlling cellular changes can enable safe rejuvenation without cancer risk.

Androgen receptors help prostate cancer cells grow and resist drugs.

Researchers converted human embryonic stem cells into trophoblast stem cells using specific transcription factors.

TRPV3 in skin cells causes inflammation and cell death.

The AVET system effectively delivers genes to human keratinocytes and may help treat skin diseases.

Modified β-catenin causes different effects in hair and skin cells, leading to cysts or tumors.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

Overexpression of E2F1 can lead to skin tumors and disrupt hair growth.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

A virus protein can activate a pathway that may lead to abnormal hair follicle development.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

A specific mutation in the TRPV3 gene causes hair follicle cells to develop improperly, leading to hair loss.

Scientists made a mouse that can be made to lose hair and then grow it back.

The study showed that a specific DNA sequence can control gene expression in hair growth areas of mice.

The early genes of a specific virus can cause abnormal skin cell growth and hair follicle changes.

Overexpressing PKCα in mice skin increases inflammation but doesn't affect tumor growth.

Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.

Transglutaminases work through a ping-pong mechanism, and human plasma and platelet transglutaminases have similar catalytic subunits.

ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.

Cells with active Wnt signaling are less likely to turn into cancer when exposed to a cancer-causing gene.