research Neonatal neurosteroid levels are determinant in shaping adult prepulse inhibition response to hippocampal allopregnanolone in rats
Neonatal neurosteroid levels affect adult brain function and behavior.
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900-930 / 1000+ resultsresearch The Biological Actions of Dehydroepiandrosterone Involves Multiple Receptors
DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
research PR-independent neurosteroid regulation of α2-GABA-A receptors in the hippocampus subfields
Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.
research Promotion of hair growth by newly synthesized ceramide mimetic compound
A new compound, BOI, can help hair grow by changing hair cycle phases and increasing certain cell contents.
research Plasma levels of C19 steroid glucuronides in pre-menopausal women with non-classical congenital adrenal hyperplasia
Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.
research 1458 EMT-inhibiting transcription factor Ovol2 regulates directional cell migration and proliferation in adult skin epithelia
Ovol2 is important for proper skin healing and hair growth.
research Ceramide synthase 4 is involved in the regulation of hair follicle stem cell homeostasis
research [Differentiated application of oral contraceptives basing on the different side effects of synthetic progestins (author's transl)].
Choose oral contraceptives with specific side effects to manage issues like acne and avoid unwanted effects.
research Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin
Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.
research The use of liposomes in the topical application of steroids
Liposomes are not better than acetone for applying DHT on skin.
research Control of androgen receptor expression in human keratinocytes and in a reconstituted human epidermis model with selective antisense oligonucleotides
Antisense oligonucleotides can reduce androgen receptor levels in skin cells, suggesting potential for treating skin disorders.
research Hippocampal 3α,5α-THP may alter depressive behavior of pregnant and lactating rats
Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.
research Alteration of neonatal Allopregnanolone levels affects exploration, anxiety, aversive learning and adult behavioural response to intrahippocampal neurosteroids
Changing Allopregnanolone levels in newborns affects adult behavior and anxiety.
research Topical Delivery of Retinyl Ascorbate
Stretching skin improves retinyl ascorbate delivery.
research Serum level of Alarin in Patients with Androgenetic Alopecia
Higher Alarin levels may predict androgenetic alopecia and metabolic syndrome.
research Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research Structural mechanism of TRPV3 channel inhibition by the plant‐derived coumarin osthole
Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
research Role of Anticonvulsant and Antiepileptogenic Neurosteroids in the Pathophysiology and Treatment of Epilepsy
Neurosteroids show promise for treating epilepsy and more research is needed.
research Intratesticular Control Of Steroidogenesis
The testes control steroid production through complex interactions involving various cells and signaling molecules.
research Studies on lysosomes—XIII
Stilbamidine and hydroxystilbamidine inhibit enzyme release from lysosomes and have effects similar to cortisol and chloroquine.
research Ethosome as a potential transdermal drug delivery system
Ethosomes are a promising way to deliver drugs through the skin.
research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
Allopregnanolone changes gene expression in glioblastoma cells.
research Östrogen-induzierte Gynäkomastie nach Anwendung östrogenhaltiger Lokaltherapeutika
Estrogen treatments can cause unwanted effects in men and should be used cautiously.
research Serum elevation of dehydroepiandrosterone sulfate associated with male pattern baldness in young men
High DHEA-S levels may cause hair loss in young men.
research THE ROLE OF ORAL SUPPLEMENTS IN MITIGATING COMMON ISOTRETINOIN SIDE EFFECTS: A COMPREHENSIVE REVIEW
Oral supplements like Vitamin E and Omega-3 can help reduce isotretinoin side effects.
research Neurosteroids Are Endogenous Neuroprotectants in an Ex Vivo Glaucoma Model
A natural steroid in the body may protect against eye damage in glaucoma.
research Omega 3 fatty acid-enriched nanoemulsion of thiocolchicoside for transdermal delivery: formulation, characterization and absorption studies
The new formulation improved the skin absorption of the drug Thiocolchicoside.
research Low-dose spironolactone in the treatment of female hirsutism.
Low-dose spironolactone is safe and effective for treating hirsutism.
research Comparison of Sequential Cyproterone Acetate/Estrogen Versus Spironolactone/Oral Contraceptive in the Treatment of Hirsutism
Both cyproterone acetate and spironolactone effectively reduce hair growth in women with hirsutism.