5 citations
,
January 2018 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” Congenital atrichia with papular lesions causes permanent hair loss in children.
2 citations
,
October 1985 in “Pediatrics in review” Scalp diseases change with age and can be hard to tell apart from hair disorders.
June 2025 in “British Journal of Dermatology” Nail abnormalities in children can indicate deeper health issues.
February 1999 in “The anatomical record” Two mouse mutants have defective hair cuticle cross-linking.
31 citations
,
September 1996 in “Differentiation” The upper dermal sheath can regenerate hair in rats.
September 2022 in “Journal of the American Academy of Dermatology” Patients with lichen planopilaris/frontal fibrosing alopecia have a higher rate of vitamin D deficiency than the general US population.
April 2025 in “Journal of Cosmetic Dermatology” The AI device accurately grades scalp exfoliation and can help diagnose scalp disorders.
September 2024 in “Cosmoderma” The young man has complete hair loss and skin bumps, with no other health issues or family history.
30 citations
,
May 2005 in “Pediatric dermatology” Some families have a genetic condition where they are born with irregular scalp defects.
August 2018 in “Pediatric Dermatology” A baby had a unique skin condition with a pale patch and surrounding dark hairs, not linked to other health issues.
1 citations
,
October 2022 in “JCI insight” Deleting the BRD4 protein in certain skin cells causes hair loss and skin inflammation.
June 2021 in “Dermatology Online Journal” A girl with a rare genetic condition affecting hair and nails also developed a common type of hair loss, suggesting a possible genetic link.
21 citations
,
June 2004 in “Experimental Dermatology” Ber‐EP4 marks cells related to the secondary hair germ in hair follicles.
108 citations
,
July 2002 in “Molecular and cellular biology” Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
49 citations
,
July 2006 in “British Journal of Dermatology” Calcifying epithelioma cells can differentiate into hair cortex and outer root sheath.
30 citations
,
January 1994 in “Micron” Mature hair surfaces are formed by keratinized cells with developed layers, not just modified plasma membranes.
13 citations
,
January 2012 in “Case reports in dermatological medicine” An 84-year-old man got a rare scalp condition from using imiquimod cream, which was cured with systemic steroids.
Spiny keratoderma is a rare skin condition with small spines on palms and soles, possibly linked to abnormal hair formation.
January 1995 in “Skin Cancer” The outer root sheath in hair follicles changes during growth, with different keratinization processes in its layers.
13 citations
,
July 2014 in “The Journal of Dermatology” Dermoscopy helped diagnose discoid lupus erythematosus in two patients without needing skin biopsies.
22 citations
,
April 1967 in “Australian Journal of Zoology” Southern elephant seals develop hair follicles and skin layers before birth, with moulting starting a week after birth and finishing in three weeks.
16 citations
,
February 2008 in “PubMed” Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.
April 2026 in “Development” Hemidesmosomes and Notch signaling help skin cells mature by moving them to the outer layer.
April 2017 in “Journal of Investigative Dermatology” April 2018 in “Dermatologic Surgery” January 2025 in “International Journal of Applied and Basic Medical Research” Effective treatment of folliculitis decalvans requires accurate diagnosis and more research for better therapies.
Whiskers can form without sensory nerves or Foxd1, thanks to Meis2 in mesenchymal cells.
Mutations in specific genes cause different types of ectodermal dysplasias.
1 citations
,
July 2021 in “Veterinary Medicine and Science” A cat's skin condition was fully cured with cyclosporine A after other treatments failed.
October 2021 in “Journal of Investigative Dermatology” The study concludes that as skin matures from infancy to childhood, there are major changes in cell differentiation, stemness, and growth, leading to a stronger skin barrier in older children.