research The Modulatable Stem Cell Niche: Tissue Interactions during Hair and Feather Follicle Regeneration
The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
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research Multi-layered environmental regulation on the homeostasis of stem cells: The saga of hair growth and alopecia
Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
research EEMCO Guidance for the Assessment of Hair Shedding and Alopecia
The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.
research Regulation of the Wound Healing Response during Aging
Aging slows wound healing due to weaker cells and immune response.
research Histopathology of aging of the hair follicle
Hair becomes gray and thin as we age, and while most hair loss in older people is due to genetics, there's a chance for gray hair to regain color under certain conditions.
research Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research Skin health and integrity
Maintaining skin health is crucial for overall well-being and involves protecting against environmental damage and using skincare products.
research Aging Skin Microbiology
research Intrinsic and Extrinsic Factors Associated with Hair Graying (Canities) and Therapeutic Potential of Plant Extracts and Phytochemicals
Plant extracts may help prevent or reverse hair graying.
research Dermal niche signaling and epidermal stem cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Melatonin Exerts Prominent, Differential Epidermal and Dermal Anti-Aging Properties in Aged Human Eyelid Skin Ex Vivo
Melatonin helps reduce aging signs in human eyelid skin.
research Sweat under surveillance: Loss of immune–metabolic loop during aging
The study by Ye et al. (2026) explores the decline of eccrine sweat glands with aging, highlighting the role of dendritic cells (DCs) as metabolic guardians. The research suggests that the disengagement of DCs from sweat gland clear cells (SGCs) during aging leads to glandular decline. In young skin, DCs support SGC metabolism through NAMPT–INSR signaling, but this support weakens with age, causing a maladaptive feedback loop. The study proposes that NAD+ supplementation and MIF–CD74 antagonists could potentially restore sweat gland function in aged skin. Despite limitations, such as the need for more direct evidence of DCs' causal role, the findings offer a new perspective on treating age-related hypohidrosis and emphasize the potential for therapeutic interventions targeting immune–metabolic interactions.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Protective Role of Melatonin and Its Metabolites in Skin Aging
Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
research Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging
Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
research The Effects of an Oral Supplementation of a Natural Keratin Hydrolysate on Skin Aging: A Randomized, Double‐Blind, Placebo‐Controlled Clinical Study in Healthy Women
Taking natural keratin supplements improved skin, hair, and nails in women.
research Regenerative Therapies for Cosmetic Dermatology for Patients with Diabetes Mellitus: Skin Aging, Aesthetic Concerns, and Evidence-Based Best Practices
A diabetes-informed approach is essential for safe and effective skin rejuvenation treatments in diabetics.
research Homoeopathic Perspectives on the Pathophysiology and Treatment of Skin Aging
research Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging
Communication between blood vessel and hair follicle cells decreases with age, affecting hair growth and blood vessel formation.
research Progress in the Development of Stem Cell-Derived Cell-Free Therapies for Skin Aging
Stem cell-derived therapies can help rejuvenate skin by improving wrinkles, elasticity, and pigmentation.
research Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels -A Narrative Review.
Collagen, curcumin, and glutathione can improve skin health in aging women with low estrogen.
research Dissecting the Impact of α-MSH-MC1R-cAMP Signaling on UVA-Induced Stress in Fibroblasts - Implications for Regulation of Cutaneous Photoaging
The α-MSH-MC1R-cAMP pathway does not protect skin cells from UVA damage.
research 364 Mechanical forces of human dermal fibroblasts significantly decrease with age
Skin cell strength decreases significantly as we age.
research Study on Antioxidants and Growth Factors in the Treatment of Alopecia with Injectables
Antioxidants and growth factors may help treat hair loss when combined with LED and Laser therapy.
research Novel approaches to characterize age‐related remodelling of the dermal‐epidermal junction in 2D, 3D and in vivo
3D imaging shows clearer details of skin structure changes with age.
research Microneedling and Oral Replacement of Collagen as Strategies for Skin Rejuvenation
Microneedling with oral collagen improves wrinkles better than microneedling alone.
research Exploration of Natural Adsorbents for Applications in Pollution-Reducing Cosmetic Formulations
Natural adsorbents in cosmetics can significantly reduce skin and hair pollution.
research Senotherapeutic Potential of Araliadiol in Senescent Human Dermal Fibroblasts: An In Vitro Study Using Three Senescence Models
Araliadiol may help reduce skin aging and inflammation without killing cells.
research Applications of Exosomal miRNAs from Mesenchymal Stem Cells as Skin Boosters
Exosomal miRNAs from stem cells can help improve skin health and delay aging.
research Cellular senescence in skin‐related research: Targeted signaling pathways and naturally occurring therapeutic agents
Targeting cellular senescence may improve skin aging and disorders.