research Data from Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of Retinoblastoma and Trp53 Tumor Suppressors
Loss of the p53 gene alone causes tumors, and losing both p53 and Rb genes speeds up aggressive skin cancer.
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research Dexpanthenol Promotes Cell Growth by Preventing Cell Senescence and Apoptosis in Cultured Human Hair Follicle Cells
Dexpanthenol helps human hair follicle cells grow by preventing aging and death, and by supporting growth signals.
research POWRÓT DO PRZESZŁOŚCI
Aging can't be stopped, but surgery can help people look younger.
research Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues
The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.
research Apoptotic dysregulation mediates stem cell competition and tissue regeneration
Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
research Mécanismes moléculaires et cellulaires des processus de différenciation et de plasticité cellulaire pour la formation des adipocytes
EGM2 and SOX2 help form beige adipocytes by maintaining ASC immaturity and activating brown adipocytes.
research Aging Alters Hair Cell Physiological Properties in Mice with Late-Onset Age-Related Hearing Loss.
Aging reduces hair cell size and function in mice, contributing to hearing loss.
research Rejuvenation by Design: Building Cosmetic Products with Extracellular Vesicle Technology, the Example of Exo.Reset®
Exo.Reset® uses extracellular vesicle technology for skin rejuvenation.
research Circadian clocks: from stem cells to tissue homeostasis and regeneration
Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
research The Influence of Age-Related Cues on Health and Longevity
Feeling younger can improve health and extend life.
research ACE2 Inhibits Dermal Regeneration Through Ang II in Tissue Expansion
Inhibiting ACE2 improves skin regeneration during tissue expansion.
research Tideglusib promotes wound healing in aged skin by activating PI3K/Akt pathway
Tideglusib helps heal wounds in older skin.
research NRF2 coordinates ferroptosis and disulfidptosis in dermal papilla cells via redox metabolic reprogramming in androgenetic alopecia
research Dissection of a Complex Enhancer Element: Maintenance of Keratinocyte Specificity but Loss of Differentiation Specificity
Keratinocyte gene expression is controlled by multiple modules with specific binding sites.
research Single‐cell transcriptomics reveals a senescence‐associated IL ‐6/ CCR6 axis driving radiodermatitis
Blocking certain immune signals can reduce skin damage from radiation therapy.
research Lineage Analysis of Epidermal Stem Cells
Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
research Diseases of the hair and scalp in the elderly
Aging can lead to poorer scalp and hair health, including less hair and more scalp diseases, which should be managed to help older people feel better.
research Quiescent and aging hair follicle stem cells
Foxc1 and COL17A1 are crucial for maintaining healthy hair follicles and preventing hair loss.
research 1407 Mechanical force activation of TGF-β signaling controls hair follicle regression
Muscle around hair follicles controls hair loss by releasing a signal that causes cell death.
research 3D co-culture model of endothelial colony-forming cells (ECFCs) reverses late passage adipose-derived stem cell senescence for wound healing
A 3D cell model can rejuvenate stem cells to improve wound healing.
research Characterization of factors that determine lentiviral vector tropism in skin tissue using an ex vivo model
Lentiviral vector effectiveness in skin is influenced by external factors, not receptor availability.
research Adipose Mesenchymal Stem Cell‐Derived Exosomes Versus Platelet‐Rich Plasma Treatment for Photoaged Facial Skin: An Investigator‐Blinded, Split‐Face, Non‐Inferiority Trial
Adipose mesenchymal stem cell-derived exosomes are as effective as platelet-rich plasma for improving photoaged skin and are a good option for those who prefer not to use needles.
research Preferential crosstalk between perifollicular capillary vessels and dermal papilla cells during hair cycling homeostasis
Capillary and dermal papilla interactions are vital for hair growth and aging, with potential for treating hair loss.
research Gynostemma pentaphyllum Hydrodistillate and Damulin B Prevent UVB‐Induced Photoaging In Vitro and In Vivo via ROS Suppression and Restoration of MAPK/AP‐1 and TGF‐β/Smad Signaling
Gynostemma pentaphyllum and Damulin B help prevent skin aging from UVB by reducing oxidative stress and improving skin health.
research Photoaging Skin Therapy with PRP and ADSC: A Comparative Study
ADSC therapy is more effective and safer for treating photoaged skin than PRP.
research A clinical study of skin changes in geriatric population
Older adults commonly experience wrinkles, itchy skin, psoriasis, fungal infections, skin growths, grey hair, hair loss, and nail ridging, but no skin cancer was found in this group.
research Involucrin: A Constituent of Cross-Linked Envelopes and Marker of Squamous Maturation
Involucrin is crucial for skin cell maturation and protection.
research Clock genes, hair growth and aging
Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.
research Epidermal and hair follicle trans glutaminases and crosslinking in skin
research 1456 Tensor effect of anigozanthos flavidus flower extract: Modulation of tenascin-X to regenerate the skin
Anigozanthos Flavidus flower extract helps regenerate skin and reduce wrinkles.