January 2018 in “Georg Thieme Verlag eBooks” Gender affirmation surgery improves personal appearance and self-esteem.
October 2024 in “Journal of the Endocrine Society” Estrogen alone can lower testosterone in some transfeminine people.
October 2025 in “Journal of the Endocrine Society” Goserelin injections can effectively manage hyperandrogenism symptoms in postmenopausal women who can't have surgery.
2170 citations
,
September 2017 in “The Journal of Clinical Endocrinology & Metabolism” A multidisciplinary approach is crucial for safe and effective hormone treatment in gender-dysphoric individuals, with specific guidelines for adolescents and adults.
October 2022 in “Journal of the ASEAN Federation of Endocrine Societies” GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.
68 citations
,
February 2019 in “Urology” Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.
20 citations
,
March 1975 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.
1 citations
,
March 2005 in “Zentralblatt für Gynäkologie” A postmenopausal woman had high testosterone from her right adrenal gland, leading to recommended surgery.
11 citations
,
November 2022 in “Journal of Endocrinological Investigation” Hormonal treatments can change hair and skin in transgender people, but may not fully achieve desired results.
98 citations
,
July 1983 in “Journal of Steroid Biochemistry” Individuals with this condition often develop male traits and identities at puberty despite being raised as females.
26 citations
,
January 2019 in “Journal of The American Academy of Dermatology” Dermatologists are important in helping transgender people with skin issues and physical changes during their transition.
September 2025 in “Medicine & Science in Sports & Exercise” Gender-affirming hormone therapy and surgery affect gut bacteria differently.
January 1983 in “Elsevier eBooks” Masculinization in affected individuals occurs gradually after puberty due to hormone changes.
1 citations
,
October 2021 in “Journal of The American Academy of Dermatology” The document concludes that treatments for hair loss in transgender and gender-diverse individuals include topical solutions, oral medications, laser therapy, and hair restoration procedures, with progress assessed after 6-12 months.
Facial hair is crucial for gender affirmation, but many face financial barriers to achieving desired results.
September 2024 in “Pediatrics in Review” Parental support and gender-affirming care are crucial for the mental health of transgender adolescents.
11 citations
,
May 2022 in “World Journal of Biological Chemistry” Progesterone may help trans women with breast development and health, but more research is needed.
1 citations
,
January 2020 in “Elsevier eBooks” Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.
November 2017 in “Dermatologic Clinics” Men are increasingly interested in cosmetic treatments that enhance masculinity and address aging without downtime, with tailored approaches for different ethnicities and a focus on hair restoration and body contouring.
176 citations
,
August 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.
9 citations
,
July 2024 in “Anaesthesia” Ensure respectful and inclusive care for transgender and gender-diverse patients during surgery.
January 2016 in “Dermatology Online Journal” Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.
204 citations
,
May 2014 in “The Journal of Sexual Medicine” Hormone therapy for trans individuals is effective and generally safe in the short term.
5 citations
,
January 2023 in “Indian Journal of Endocrinology and Metabolism” The statement offers guidance for hormone therapy and surgery to help gender-incongruent adults affirm a male identity.
25 citations
,
September 2014 in “Pharmacotherapy” Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.
48 citations
,
January 2005 in “Treatments in Endocrinology” June 2009 in “マテリアルインテグレ-ション” Men's cosmetic procedures need to consider male-specific differences for better results.
37 citations
,
January 2009 in “Sexual Development” Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
January 2026 in “Clinics in Dermatology” Managing menopause symptoms like skin changes and hair thinning involves hormone therapy, procedures, and skincare, with emotional support being important.
January 2026 in “JCEM Case Reports” Genetics may play a significant role in gender dysphoria.