research Ruolo dei neurosteroidi nella modulazione dopaminergica
Neurosteroids help control dopamine responses in the brain.
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450-480 / 1000+ resultsresearch Author response: Structural basis of malodour precursor transport in the human axilla
The transporter protein SH1446 in Staphylococcus hominis is key to underarm odor production.
research Highly flexible and controllable hierarchical MOF membrane for efficient drug release
research Ellagic acid inhibits dihydrotestosterone-induced ferroptosis and promotes hair regeneration by activating the Wnt/β-catenin signaling pathway
Ellagic acid may help regrow hair and prevent hair loss by activating a specific cell growth pathway.
research MP09-17 METHYLATION OF SRD5A2 IN THE BLOOD AS A NOVEL BIOMARKER TO PREDICT SENSITIVITY TO 5-ARI TREATMENT
SRD5A2 methylation in blood can predict how well someone will respond to finasteride treatment.
research Mesenchymal stromal cells in hepatic fibrosis/cirrhosis: from pathogenesis to treatment
research Possible involvement of 5α-reduced neurosteroids in adrenergic and serotonergic stimulation of GFAP gene expression in rat C6 glioma cells
5α-reduced neurosteroids may help regulate glial cell differentiation.
research Farmácia Lemos, Porto e Serviços Farmacêuticos da Unidade Local de Saúde de Matosinhos, EPE (Hospital Pedro Hispano), Senhora da Hora
Pharmacists play a crucial role in personalized care and medication management.
research Administration of finasteride modulates depressive-like behavior in the forced swim task of male rats
research The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis
mTOR inhibitors may help treat lung fibrosis.
research Cyclodextrins as excipients in solid oral dosage forms
research Neonatal allopregnanolone or finasteride administration modifies hippocampal K+ Cl− co-transporter expression during early development in male rats
Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.
research IRF2BP2 genes provide new insights into coat type and fiber composition variation in sheep
The IRF2BP2 gene affects sheep fleece quality by influencing fiber traits.
research FGF Family: From Drug Development to Clinical Application
FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
research Molecular mechanism for transcriptional regulation of the parathyroid hormone gene by Epiprofin
Epiprofin suppresses parathyroid hormone gene activity, helping regulate calcium levels and could be a treatment target for hyperparathyroidism.
research Serum ferritin levels and Diffuse hair loss—A correlation
Low serum ferritin levels are significantly linked to diffuse hair loss.
research Editorial highlights
Recent advances show zebrafish can model anemia, Alx4 affects craniofacial and hair development, and mTORC1 is crucial for retinal development.
research Targeting the (Un)differentiated State of Cancer
Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.
research The assessment of knowledge and awareness about iron deficiency anemia among the population of Riyadh province
More awareness and education on iron deficiency anemia are needed in Riyadh.
research Shifting IRES versus Cap-initiated translation during homeostatic stem cell differentiation and stress
Caloric stress and differentiation increase IRES translation, affecting stem cell function and potential therapies.
research RNA-seq analysis identifies key genes enhancing hoof strength to withstand barefoot racing in Standardbred trotters
Certain genes contribute to stronger hooves in barefoot racing horses.
research MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters
MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.
research Probing androgen receptor co-factor selectivity profiles: a chemical tool to determine cross-talk between androgen receptor and β-catenin in vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Farmácia dos Clérigos - Porto e nos Serviços Farmacêuticos da University College Hospital - Londres, Reino Unido, ao abrigo do programa Erasmus+
Pharmacists play a crucial role in improving patient outcomes through personalized care and staying updated with scientific advancements.
research The activin binding proteins follistatin and follistatin-related protein are differentially regulated in vitro and during cutaneous wound repair
FLRG and follistatin have different roles in wound healing.
research A computer‐aided drug repurposing: the antibacterial agents targeting GroEL
Daprodustat, combined with PAβN, could be a new antibacterial treatment.
research The Diagnostic Value of Serum Ferritin for Telogen Effluvium: A Cross-Sectional Comparative Study
Low iron levels in the blood could be a sign of Telogen Effluvium, a type of hair loss, but it's not always accurate in distinguishing it from other hair loss types.
research Charting the Bromodomain BRD4: Towards the Identification of Novel Inhibitors with Molecular Similarity and Receptor Mapping
Researchers identified promising inhibitors for the BRD4 protein, including finasteride and amentoflavone.
research A Case of Delusional Parasitosis Secondary to Severe Iron Deficiency Anaemia in a Tertiary Care Hospital: An Area for Clinical Vigilance
Iron deficiency can cause psychiatric symptoms that improve with proper treatment.
research 899 HIF1A stabilisation in the ORS of human hair follicles promotes aerobic glycolysis and synthesis of angiogenic factors
Stabilizing HIF1A in hair follicles may boost hair growth by enhancing energy production and blood vessel formation.