8 citations
,
February 2014 in “General and Comparative Endocrinology” Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
6 citations
,
June 2016 in “Experimental Dermatology” Frontal Fibrosing Alopecia is a poorly understood condition that is hard to treat and causes distressing hair loss.
2 citations
,
June 2019 in “Boletín médico del Hospital Infantil de México” Tofacitinib treatment is used for teenagers with alopecia areata.
10 citations
,
June 2020 in “Journal of Cosmetic Dermatology” Frontal fibrosing alopecia may be linked to genital Lichen sclerosus through an autoimmune process.
August 2021 in “Research Square (Research Square)” Ferulic acid can reduce seizures and depression-like behaviors in catamenial epilepsy by balancing hormones and brain enzyme activity.
October 2025 in “Journal of the Endocrine Society” Low estrogen due to poor nutrition can lead to non-alcoholic fatty liver disease.
January 2022 in “Дерматологія та венерологія” Frontal fibrosing alopecia causes hair loss along the frontal hairline, mainly in postmenopausal women, and needs better treatments.
July 2015 in “Journal of the Dermatology Nurses’ Association” A 66-year-old woman experienced hair loss due to Frontal Fibrosing Alopecia, a condition with no consistently effective treatment, but it usually stabilizes over time. More research is needed for better understanding and treatment options.
119 citations
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November 2014 in “Trends in Cell Biology” Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
9 citations
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August 2021 in “Biomedicines” 17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.
29 citations
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May 1988 in “Clinical Endocrinology” Fibroblasts help understand androgen resistance at the cellular level.
29 citations
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July 2010 in “Journal of Cutaneous Medicine and Surgery” Treatments for Frontal Fibrosing Alopecia have not been proven effective.
April 2009 in “The FASEB Journal” More research is needed on the safety of fathers' drug exposure before conception.
2 citations
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February 2023 in “Anais Brasileiros de Dermatologia”
8 citations
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October 2019 in “International Journal of Dermatology” The study concluded that combination therapy with topical corticosteroids and hydroxychloroquine or finasteride is effective in treating Frontal fibrosing alopecia in Asians.
1 citations
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June 2025 in “Frontiers in Genetics” Key genes IRF2BP2 and EGFR are linked to Hetian sheep's double-coat fleece.
76 citations
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July 2009 in “Neuroscience” Neurosteroids like allopregnanolone help control cell death and growth in the developing fetal brain.
September 2025 in “Development” Nelfb is crucial for forming skin fat tissue by regulating genes needed for fat cell development.
1 citations
,
June 2017 in “Actas Dermo-Sifiliográficas” Follicular Unit Extraction (FUE) is a hair transplant method with less scarring and discomfort but requires skilled surgeons and has limitations on graft numbers per session.
2 citations
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January 2023 in “Biomedicines” The treatment combining laser and fetal fibroblasts effectively reduces scarring.
July 2024 in “Reactions Weekly”
7 citations
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June 2015 in “The anatomical record” Hexi cashmere goats' hair growth varies by stage, with Hoxc13 linked to hair activity.
5 citations
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January 2016 in “European Journal of Dermatology” Suplatast tosilate successfully treated a woman's systemic sclerosis symptoms.
19 citations
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January 2023 in “Genes” Certain genes influence wool, growth, and reproduction traits in Uruguayan Merino sheep.
16 citations
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January 2017 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Managing frontal fibrosing alopecia and lichen planus pigmentosus is challenging due to resistant hair loss and skin discoloration.
20 citations
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January 2016 in “Intractable & Rare Diseases Research” Combination therapy, especially with finasteride, is effective for treating frontal fibrosing alopecia.
3 citations
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November 2017 in “International Journal of Pharmacy and Pharmaceutical Sciences” 34 citations
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July 2020 in “American journal of human genetics” Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.
50 citations
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September 2012 in “Developmental Biology” Sprouty and FGF balance is crucial for normal feather shape and size.