January 2026 in “Burns & Trauma” RNA modifications help heal wounds and could lead to new treatments.
14 citations
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July 2022 in “Applied Sciences” Extracellular vesicles can help repair and regenerate tissues with less risk of rejection.
2 citations
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June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Epigenetic factors play a crucial role in skin health and disease.
July 2025 in “Cosmoderma” PRP therapy has evolved over 70 years and is used for healing and cosmetic purposes, but its effectiveness varies.
April 2026 in “International Journal of Nanomedicine” Quercetin delivery systems are improving its effectiveness for medical use.
182 citations
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June 2017 in “Biomaterials” Special fiber materials boost the healing properties of certain stem cells.
187 citations
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April 2019 in “npj Regenerative Medicine” Wharton's jelly secretomes are best for promoting blood vessel growth.
June 2026 in “Discover Immunity.” Mesenchymal stem cells (MSCs) are promising for skin repair and rejuvenation due to their regenerative, anti-inflammatory, and immunomodulatory properties. This review highlights MSCs from neonatal sources like the placenta and umbilical cord for their availability and scalability. MSCs aid skin repair through paracrine mechanisms, enhancing collagen production, reducing inflammation, and promoting cell growth. Clinical studies, including a meta-analysis of 55 trials with 2,696 patients, show MSCs' safety and efficacy in improving wound healing and skin conditions. Despite challenges like delivery optimization and reduced efficacy over time, MSC-based therapies, including MSC-derived extracellular vesicles and biomaterial-assisted delivery, show potential in regenerative and aesthetic applications.
June 2026 in “Journal of Biological Engineering” Stem cell therapies are advancing quickly with new technologies and need supportive regulations for clinical use.
January 2026 in “Frontiers in Immunology” Icariin can regulate macrophages and may help treat inflammation, cancer, bone disorders, and fibrotic diseases.
January 2026 in “Asian Journal of Pharmaceutical and Clinical Research” Umbilical cord and cord blood stem cells are promising for treating chronic diseases due to their versatility and ethical acceptability.
11 citations
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January 2022 in “Theranostics” Wnt4 is essential for heart repair and could be a target for heart disease treatment.
76 citations
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February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
6 citations
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March 2021 in “Cytotechnology” Mesenchymal stem cells show promise in treating COVID-19 by reducing inflammation and aiding recovery, but more research is needed.
1 citations
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January 2023 in “Burns and trauma” Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.
October 2023 in “Frontiers in endocrinology” Effective PCOS treatments require targeting specific signaling pathways.
Tiny particles called extracellular vesicles show potential for improving skin health in cosmetics, but more research is needed to confirm their safety and effectiveness.
76 citations
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July 2019 in “Cellular and Molecular Life Sciences” Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
9 citations
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April 2025 in “Stem Cell Research & Therapy” MSC-derived conditioned media can improve skin treatments.
26 citations
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July 2021 in “Frontiers in Cell and Developmental Biology” The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.
5 citations
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April 2024 in “Journal of Ovarian Research” miR-21 helps improve ovarian function recovery in treated mice.
September 2019 in “Journal of Investigative Dermatology” Silibinin may help promote hair growth and treat hair loss.
December 2023 in “Regenerative therapy” miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
April 2026 in “Frontiers in Physiology” Polygonum multiflorum root nanovesicles may help hair growth and treat hair loss.
September 2024 in “Stem Cell Research & Therapy” HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.
29 citations
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December 2022 in “Journal of Nanobiotechnology” Stem cell vesicles reduced eczema symptoms in mice safely.
6 citations
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July 2022 in “World journal of stem cells” Using extracellular vesicles from stem cells can help hair grow by affecting scalp cells and hair follicles.
2 citations
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November 2025 in “International Journal of Molecular Sciences” Chitosan-based materials are promising for treating diseases and healing wounds due to their beneficial properties.
2 citations
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September 2025 in “International Journal of Nanomedicine” Extracellular vesicles can help treat skin issues like wounds, hair loss, aging, and inflammation.
13 citations
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January 2024 in “Journal of Nanobiotechnology” The new wound dressing improves healing and tissue repair better than conventional dressings.